Evidence map›Paper›PMID 24408044›Full record

ArticleLa Radiologia medica2014

CT enterography as a powerful tool for the evaluation of inflammatory activity in Crohn's disease: relationship of CT findings with CDAI and acute-phase reactants.

Giuseppe Lo Re, Maria Cappello, Chiara Tudisca, Massimo Galia, Claudia Randazzo, Antonio Craxì, Calogero Cammà, Andrea Giovagnoni, Massimo Midiri

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In one paragraph

Article in La Radiologia medica, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Imaging of Bowel Lymphoma: A Pictorial Review.Digestive diseases and sciences · 2022
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  7. Advances in diagnostic and interventional radiology.Acta bio-medica : Atenei Parmensis · 2019
    Article
  8. Review
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  12. Observational
  13. Errors in imaging patients in the emergency setting.The British journal of radiology · 2016
    Review
  14. Radiological Features of Gastrointestinal Lymphoma.Gastroenterology research and practice · 2016
    Review
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Giuseppe Lo ReSezione di Scienze Radiologiche, Dipartimento di Biopatologia e Biotecnologie Mediche e Forensi (DIBIMEF), Azienda Ospedaliera Policlinico Paolo Giaccone, Via del Vespro, 129, 90127, Palermo, Italy.
Maria Cappello
Chiara Tudisca
Massimo Galia
Claudia Randazzo
Antonio Craxì
Calogero Cammà
Andrea Giovagnoni
Massimo Midiri
Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo · ITOspedali Riuniti di Ancona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFew studies have correlated computed tomography enterography (CTE) findings with Crohn's disease (CD) clinical and biochemical activity. The aim of this study was to evaluate correlations between CTE findings with CD activity. MATERIALS AND

methodsThe CTE datasets from 62 patients were retrospectively reviewed for different parameters: bowel wall thickening and hyperenhancement, mesenteric alterations, abdominal free fluid and complications related to the disease (fistulas, strictures, abscesses). Activity was assessed using the Crohn's Disease Activity Index (CDAI) and some biochemical markers (C-reactive protein, erythrocyte sedimentation rate, alpha 2-globulins, fibrinogen, platelets, haemoglobin). Correlations between CTE parameters, clinical activity score and laboratory parameters were assessed by logistic regression.

resultsCDAI was significantly correlated with increased fat density (p = 0.03) and intestinal strictures (p = 0.04). Platelet counts were elevated in patients with enlarged mesenteric lymph nodes (p = 0.009) and the comb sign (p = 0.05). Serum alpha 2-globulins were higher in the presence of the comb sign (p = 0.03).

conclusionThe CTE finding of perienteric inflammation (increased fat density) and vascular engorgement of the vasa recta in CD patients suggest that the disease is clinically active and that these patients may require more aggressive treatment than patients without these findings.

Indexed as

Tomography, X-Ray ComputedAdultBiomarkersBlood SedimentationC-Reactive ProteinCrohn DiseaseFemaleFibrinogenHemoglobinsHumansInflammationIntestine, SmallLogistic ModelsLymph NodesMalePlatelet CountBiomarkersC-Reactive ProteinFibrinogenHemoglobins

Identifiers

PMID24408044
OpenAlexW2072769547

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.