ArticleGenome research2014
A long-term demasculinization of X-linked intergenic noncoding RNAs in Drosophila melanogaster.
Article in Genome research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Genomic survey of high-throughput RNA-Seq data implicates involvement of long intergenic non-coding RNAs (lincRNAs) in cytoplasmic male-sterility and fertility restoration in pigeon pea.Genes & genomics · 2023Article
- A putative de novo evolved gene required for spermatid chromatin condensation in Drosophila melanogaster.PLoS genetics · 2021Article
- Sex Chromosome-wide Transcriptional Suppression and Compensatory Cis-Regulatory Evolution Mediate Gene Expression in the Drosophila Male Germline.PLoS biology · 2016Article
- Comparative Expression Dynamics of Intergenic Long Noncoding RNAs in the Genus Drosophila.Genome biology and evolution · 2016Article
- Dosage Compensation and the Distribution of Sex-Biased Gene Expression in Drosophila: Considerations and Genomic Constraints.Journal of molecular evolution · 2016Article
- Spermatogenesis Drives Rapid Gene Creation and Masculinization of the X Chromosome in Stalk-Eyed Flies (Diopsidae).Genome biology and evolution · 2016Article
- Poised chromatin and bivalent domains facilitate the mitosis-to-meiosis transition in the male germline.BMC biology · 2015Article
- Genetic and epigenetic architecture of sex-biased expression in the jewel wasps Nasonia vitripennis and giraulti.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Variation in the X:Autosome Distribution of Male-Biased Genes among Drosophila melanogaster Tissues and Its Relationship with Dosage Compensation.Genome biology and evolution · 2015Article
- Genome-wide identification, characterization and evolutionary analysis of long intergenic noncoding RNAs in cucumber.PloS one · 2015Article
- Volatile evolution of long noncoding RNA repertoires: mechanisms and biological implications.Trends in genetics : TIG · 2014Review
- Population- and sex-biased gene expression in the excretion organs of Drosophila melanogaster.G3 (Bethesda, Md.) · 2014Article
- PLEK: a tool for predicting long non-coding RNAs and messenger RNAs based on an improved k-mer scheme.BMC bioinformatics · 2014Article
- Article
- Sex-biased expression of microRNAs in Drosophila melanogaster.Open biology · 2014Article
- De novo assembly and transcriptome analysis of the Mediterranean fruit fly Ceratitis capitata early embryos.PloS one · 2014Article
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Authors and funding
12 authors.
Funding
Abstract
Recent studies have revealed key roles of noncoding RNAs in sex-related pathways, but little is known about the evolutionary forces acting on these noncoding RNAs. Profiling the transcriptome of Drosophila melanogaster with whole-genome tiling arrays found that 15% of male-biased transcribed fragments are intergenic noncoding RNAs (incRNAs), suggesting a potentially important role for incRNAs in sex-related biological processes. Statistical analysis revealed a paucity of male-biased incRNAs and coding genes on the X chromosome, suggesting that similar evolutionary forces could be affecting the genomic organization of both coding and noncoding genes. Expression profiling across germline and somatic tissues further suggested that both male meiotic sex chromosome inactivation (MSCI) and sexual antagonism could contribute to the chromosomal distribution of male-biased incRNAs. Comparative sequence analysis showed that the evolutionary age of male-biased incRNAs is a significant predictor of their chromosomal locations. In addition to identifying abundant sex-biased incRNAs in the fly genome, our work unveils a global picture of the complex interplay between noncoding RNAs and sexual chromosome evolution.
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