Evidence map›Paper›PMID 24407716›Full record

ReviewPaediatric drugs2014

Postoperative pain management in children and infants: an update.

Christopher Brasher, Benjamin Gafsous, Sophie Dugue, Anne Thiollier, Joelle Kinderf, Yves Nivoche, Robert Grace, Souhayl Dahmani

4 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Paediatric drugs, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 37 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 5 pooled it
6.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02236130 naterminatednot on this map

Peripheral Nerve Blocks in Pediatric Orthopedic Patients: Are There Any Post Recovery Benefits?

TypeinterventionalSponsorUniversity of Mississippi Medical CenterRan2014 to 2015Enrolled49ConditionsPediatric Extremity Fracture, Pediatric Extremity Soft Tissue InjuryArmsRegional block, General Anesthesia, Local Anesthetic Ropivacaine, Opioids Morphine, Oral pain medication Acetaminophen with Hydrocodone
NCT02563587 naunknown statusnot on this mapstarted 2015, after this paper: background citation

Efficacy of the Spontaneous Laughter on Postoperative Pain and Anxiety in Children. A Randomized Controlled Trial

TypeinterventionalSponsorHospital General Naval de Alta Especialidad - Escuela Medico NavalRan2015 to 2018Enrolled210ConditionsPainArmsLaughter therapy, Accompaniment without causing the laughter of children., Conventional treatment
NCT02789969 naunknown statusnot on this mapstarted 2016, after this paper: background citation

A Randomized Controlled Trial to Compare Pain Medications in Children Undergoing Strabismus Surgery

TypeinterventionalSponsorSt. Louis Children's HospitalRan2016 to 2017Enrolled128ConditionsPain, NauseaArmsHydromorphone, Fentanyl
NCT06988748 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

The Effect of Tonsillectomy Diet Education on Bleeding and Pain After Adenotonsillectomy in Children

TypeinterventionalSponsorMaltepe UniversityRan2025 to 2026Enrolled76ConditionsAdenotonsillar HypertrophyArmsAssigned Interventions (diet training)
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 5 syntheses or guidelines pooled it, 105 citations in OpenAlex.

  1. Pooled it
  2. Ibuprofen for acute postoperative pain in children.The Cochrane database of systematic reviews · 2024
    Pooled it
  3. Single-dose intravenous ibuprofen for acute postoperative pain in adults.The Cochrane database of systematic reviews · 2021
    Pooled it
  4. Single-dose intravenous ketorolac for acute postoperative pain in adults.The Cochrane database of systematic reviews · 2021
    Pooled it
  5. Ketorolac for postoperative pain in children.The Cochrane database of systematic reviews · 2018
    Pooled it
  6. Trial
  7. Opioid Analgesia Following Pediatric Adenotonsillectomy: A Randomized Clinical Trial.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025
    Trial
  8. Trial
  9. Trial
  10. Evaluating Caudal Block Enhancements in Pediatric Circumcision: Do Additional Analgesics Make a Difference?Medical science monitor : international medical journal of experimental and clinical research · 2023
    Trial
  11. Trial
  12. Trial
  13. Article
  14. Postoperative pain management in children.Frontiers in pediatrics · 2026
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Christopher BrasherDepartment of Anesthesiology, Intensive Care, Robert Debré Hospital, 48 Bd Sérurier, 75019, Paris, France.
Benjamin Gafsous
Sophie Dugue
Anne Thiollier
Joelle Kinderf
Yves Nivoche
Robert Grace
Souhayl Dahmani
Hôpital Robert-Debré · FRUniversité Paris Cité · FRCairns Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many factors contribute to suboptimal pain management in children. Current evidence suggests that severe pain in children has significant long-lasting effects, even more so than in adults. In particular, recent evidence suggests a lack of optimal postoperative pain management in children, especially following ambulatory surgery. This review provides simple guidelines for the management of postoperative pain in children. It discusses the long-term effects of severe pain and how to evaluate pain in both healthy and neurologically impaired children, including neonates. Currently available treatment options are discussed with reference to the efficacy and side effects of opioid and non-opioid and regional analgesic techniques. The impact of preoperative anxiety on postoperative pain, and the efficacy of some nonpharmacological techniques such as hypnosis or distraction, are also discussed. Finally, basic organizational strategies are described, aiming to promote safer and more efficient postoperative pain management in children.

Indexed as

Adrenergic alpha-2 Receptor AgonistsAnalgesiaAnalgesicsAnti-Inflammatory Agents, Non-SteroidalChildHumansInfantPain ManagementPostoperative PainAdrenergic alpha-2 Receptor AgonistsAnalgesicsAnti-Inflammatory Agents, Non-Steroidal

Identifiers

PMID24407716
OpenAlexW2025921033

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.