Evidence map›Paper›PMID 24407538›Full record

ReviewIndian heart journal2013

The nuances of atherogenic dyslipidemia in diabetes: focus on triglycerides and current management strategies.

P C Manoria, H K Chopra, S K Parashar, A L Dutta, Brian Pinto, Ajit Mullasari, Samir Prajapati

Open access · goldAbstract readReview
In one paragraph

Review in Indian heart journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Glycoprotein Profile Measured by aLife (Basel, Switzerland) · 2021
    Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 1 country.

P C ManoriaDirector, Manoria Heart Care & Critical Care Hospital, Bhopal, India.
H K ChopraSr. Consultant Cardiologist, Moolchand Medcity, New Delhi 19, India. Electronic address: drhkchopra@gmail.com.
S K ParasharSr. Consultant Cardiologist, Metro Heart Institute, New Delhi, India.
A L DuttaProf., Cardiology, Vivekananda Institute of Medical Sciences, Kolkata, India.
Brian PintoChief Cardiologist, Holy Family Hospital, Mumbai, India.
Ajit MullasariDirector, Cardiology, Institute of Cardio Vascular Diseases, Madras Medical Mission, Chennai, India.
Samir PrajapatiMedical Advisor, Cadila Healthcare, Ahmedabad, India.
Apex Heart Institute · INAster Medcity · INCadila Healthcare (India) · INCARE Hospitals · INHoly Family Hospital · INMadras Medical Mission · INVivekananda Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus (DM) is a pandemic disease and an important cardiovascular (CV) risk factor. The atherogenic dyslipidemia in diabetes (ADD) is characterized by high serum triglycerides, high small dense LDL levels, low HDL levels and postprandial lipemia. Insulin resistance is a primary cause for ADD. Though statins are highly effective for CVD prevention in DM but a significant residual CV risk remains even after optimal statin therapy. Fibrates, niacin and omega-3 fatty acids are used in addition to statin for treatment of ADD (specifically hypertriglyceridemia). All these drugs have some limitations and they are far from being ideal companions of statins. Many newer drugs are in pipeline for management of ADD. Dual PPAR α/γ agonists are in most advanced stage of clinical development and they have a rational approach as they control blood glucose levels (by reducing insulin resistance, a primary factor for ADD) in addition to modulating ADD. Availability of dual PPAR α/γ agnosits and other drugs for ADD management may improve CV outcomes and decrease morbidity and mortality in diabetic patients in future.

Indexed as

Disease ManagementAtherosclerosisComorbidityDiabetes Mellitus, Type 2Diabetic AngiopathiesDyslipidemiasFemaleFollow-Up StudiesHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleNiacinRisk FactorsSeverity of Illness IndexSurvival RateTreatment OutcomeHydroxymethylglutaryl-CoA Reductase InhibitorsNiacinTriglyceridesAtherogenic dyslipidemia in diabetesDual PPAR alpha and gamma agonistsHypertriglyceridemiaSaroglitazar

Identifiers

PMID24407538
PMCPMC3905264
OpenAlexW1973237182

What OpenQuestion holds

Texttitle and abstract
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.