ArticleIndian heart journal2013
Lipoprotein lipase gene HindIII polymorphism and risk of myocardial infarction in South Indian population.
Article in Indian heart journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Lipoprotein Lipase (LPL) Polymorphism and the Risk of Coronary Artery Disease: A Meta-Analysis.International journal of environmental research and public health · 2017Pooled it
- Associations of the PPARα and Lipoprotein Lipase Enzyme Gene Polymorphisms with Dyslipidemia in Obese and Non-obese Males.Journal of obesity & metabolic syndrome · 2024Article
- Age Stratification in Genetic Variation of Lipoprotein Lipase in Metabolic Syndrome Javanese Ethnics of Indonesia.Open access Macedonian journal of medical sciences · 2019Article
- The Association of a Rare Variant of -93, -53 Promoter Gene Polymorphisms of Lipoprotein Lipase gene with Obesity and Insulin Resistance.Oman medical journal · 2018Article
- Associations betweenBioscience reports · 2018Article
- Impact of Lipoprotein Lipase Gene Polymorphism, S447X, on Postprandial Triacylglycerol and Glucose Response to Sequential Meal Ingestion.International journal of molecular sciences · 2016Article
- The Association of Lipoprotein Lipase Genes, HindIII and S447X Polymorphisms With Coronary Artery Disease in Shiraz City.Journal of cardiovascular and thoracic research · 2015Article
- Review
- Multilocus Analysis of Genetic Susceptibility to Myocardial Infarction in Russians: Replication Study.Acta naturaeArticle
- Association of the lipoprotein lipase and Apolipoprotein C-II gene polymorphisms with risk of dyslipidemia in smokers and non-smokers male.Indian heart journalArticle
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionStudies have reported an association between lipoprotein lipase (LPL) gene and myocardial infarction in some populations. Therefore, the present study aimed to investigate the association of the HindIII polymorphism of the (LPL) gene with myocardial infarction and to explore its potential role in susceptibility in a South Indian population. SUBJECTS AND
methodsWe included a total of 412 subjects (202 myocardial infarction patients and 210 age- and sex-matched controls). Demographic and clinical characteristics were collected. Lipid profiles were estimated. DNA was isolated and the LPL gene HindIII polymorphism was determined by polymerase chain reaction.
resultsComparison of the lipid profiles between patients and controls showed that patients had statistically high significant values (p = 0.0001). The H(+) H(+) genotype of the LPL gene is associated with myocardial infarction. H(+) H(+) vs. H(-) H(-) was χ2 = 19.4, OR 3.1, CI 95% 1.8-5.2, p < 0.0001.
conclusionOur study strongly suggests that the LPL gene HindIII Hþ Hþ genotype is an independent risk factor for first MI.
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