ArticleCell research2014
Digital response in T cells: to be or not to be.
Article in Cell research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Engineered CD4 T cells for in vivo delivery of therapeutic proteins.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Primary T-cell-based delivery platform for in vivo synthesis of engineered proteins.Bioengineering & translational medicine · 2024Article
- Temporal signaling, population control, and information processing through chromatin-mediated gene regulation.Journal of theoretical biology · 2022Article
- Role of the JAK/STAT Pathway in Cervical Cancer: Its Relationship with HPV E6/E7 Oncoproteins.Cells · 2020Review
- Structural understanding of T cell receptor triggering.Cellular & molecular immunology · 2020Review
- Elastomeric sensor surfaces for high-throughput single-cell force cytometry.Nature biomedical engineering · 2018Article
- Simulation of Stimulation: Cytokine Dosage and Cell Cycle Crosstalk Driving Timing-Dependent T Cell Differentiation.Frontiers in physiology · 2018Article
- The Maintenance of Telomere Length in CD28+ T Cells During T Lymphocyte Stimulation.Scientific reports · 2017Article
- Longitudinal multiparameter assay of lymphocyte interactions from onset by microfluidic cell pairing and culture.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Negative regulation of TCR signaling by ubiquitination of Zap-70 Lys-217.Molecular immunology · 2016Article
- Inferring the Effects of Honokiol on the Notch Signaling Pathway in SW480 Colon Cancer Cells.Cancer informatics · 2014Article
Corrections and comments
- Comment on
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A recent study published in Immunity shows that foreign antigens elicit all-or-nothing T cell responses and that a single antigen is enough to trigger this digital cytokine secretion.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.