ArticleLab on a chip2014
Standing surface acoustic wave (SSAW)-based microfluidic cytometer.
Article in Lab on a chip, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 123 citations in OpenAlex.
- Driving Rotational Circulation in a Microfluidic Chamber Using Dual Focused Surface-Acoustic-Wave Beams.Micromachines · 2025Article
- Spatial regulation of hydrogel polymerization reaction using ultrasound-driven streaming vortex.Ultrasonics sonochemistry · 2024Article
- Essential Fluidics for a Flow Cytometer.Current protocols · 2024Article
- Optofluidic Flow Cytometer with In-Plane Spherical Mirror for Signal Enhancement.Sensors (Basel, Switzerland) · 2023Article
- Bacterial Concentration Detection using a PCB-based Contactless Conductivity Sensor.Micromachines · 2019Article
- Applications of Acoustofluidics in Bioanalytical Chemistry.Analytical chemistry · 2019Article
- Standing Surface Acoustic Wave (SSAW)-Based Fluorescence-Activated Cell Sorter.Small (Weinheim an der Bergstrasse, Germany) · 2018Article
- Microfluidic-Based Single-Cell Study: Current Status and Future Perspective.Molecules (Basel, Switzerland) · 2018Review
- Microparticle Manipulation by Standing Surface Acoustic Waves with Dual-frequency Excitations.Journal of visualized experiments : JoVE · 2018Article
- Smart Cell Culture Systems: Integration of Sensors and Actuators into Microphysiological Systems.ACS chemical biology · 2018Review
- A sharp-edge-based acoustofluidic chemical signal generator.Lab on a chip · 2018Article
- Microfluidic flow cytometry: The role of microfabrication methodologies, performance and functional specification.Technology · 2018Article
- Vertical Hydrodynamic Focusing and Continuous Acoustofluidic Separation of Particles via Upward Migration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2018Article
- Force-Mediating Magnetic Nanoparticles to Engineer Neuronal Cell Function.Frontiers in neuroscience · 2018Review
- Sheathless Microflow Cytometry Using Viscoelastic Fluids.Scientific reports · 2017Article
- Particle separation by phase modulated surface acoustic waves.Biomicrofluidics · 2017Article
- Acoustic actuation of bioinspired microswimmers.Lab on a chip · 2017Article
- Enriching Nanoparticles via Acoustofluidics.ACS nano · 2017Article
- Surface acoustic wave devices for chemical sensing and microfluidics: A review and perspective.Analytical methods : advancing methods and applications · 2017Article
- Modeling of Microdevices for SAW-Based Acoustophoresis - A Study of Boundary Conditions.Micromachines · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
The development of microfluidic chip-based cytometers has become an important area due to their advantages of compact size and low cost. Herein, we demonstrate a sheathless microfluidic cytometer which integrates a standing surface acoustic wave (SSAW)-based microdevice capable of 3D particle/cell focusing with a laser-induced fluorescence (LIF) detection system. Using SSAW, our microfluidic cytometer was able to continuously focus microparticles/cells at the pressure node inside a microchannel. Flow cytometry was successfully demonstrated using this system with a coefficient of variation (CV) of less than 10% at a throughput of ~1000 events s(-1) when calibration beads were used. We also demonstrated that fluorescently labeled human promyelocytic leukemia cells (HL-60) could be effectively focused and detected with our SSAW-based system. This SSAW-based microfluidic cytometer did not require any sheath flows or complex structures, and it allowed for simple operation over a wide range of sample flow rates. Moreover, with the gentle, bio-compatible nature of low-power surface acoustic waves, this technique is expected to be able to preserve the integrity of cells and other bioparticles.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.