ArticleAIDS (London, England)2014
CD4+ cell count at antiretroviral therapy initiation and economic restoration in rural Uganda.
Article in AIDS (London, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Reliability and validity of depression assessment among persons with HIV in sub-Saharan Africa: systematic review and meta-analysis.Journal of acquired immune deficiency syndromes (1999) · 2014Pooled it
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- Trial
- Intergenerational spillover effects of antiretroviral therapy in sub-Saharan Africa: a scoping review and future directions for research.BMJ global health · 2023Article
- Internalized stigma, depressive symptoms, and the modifying role of antiretroviral therapy: A cohort study in rural Uganda.SSM. Mental health · 2021Article
- HIV-related stigma trends in the general population of India during an era of antiretroviral treatment expansion, 2005-16.Journal of global health · 2020Article
- High viral suppression and low attrition in healthy HIV-infected patients initiated on ART with CD4 above 500 cells/µL in a program setting in Uganda.African health sciences · 2020Article
- Trajectories of HIV-related internalized stigma and disclosure concerns among ART initiators and non-initiators in South Africa.Stigma and health · 2019Article
- Task-shifting alcohol interventions for HIV+ persons in Kenya: a cost-benefit analysis.BMC health services research · 2017Article
- The economic benefits of high CD4 counts among people living with HIV/AIDS in Zambia.Journal of public health (Oxford, England) · 2016Article
- A livelihood intervention to improve economic and psychosocial well-being in rural Uganda: Longitudinal pilot study.SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance · 2016Article
- HIV stigma trends in the general population during antiretroviral treatment expansion: analysis of 31 countries in sub-Saharan Africa, 2003-2013.Journal of acquired immune deficiency syndromes (1999) · 2016Article
- Understanding Sustained Retention in HIV/AIDS Care and Treatment: a Synthetic Review.Current HIV/AIDS reports · 2016Review
- HIV Treatment Scale-Up and HIV-Related Stigma in Sub-Saharan Africa: A Longitudinal Cross-Country Analysis.American journal of public health · 2015Article
- Socioeconomic gradients in internalized stigma among 4,314 persons with HIV in sub-Saharan Africa.AIDS and behavior · 2015Article
- Persistent HIV-related stigma in rural Uganda during a period of increasing HIV incidence despite treatment expansion.AIDS (London, England) · 2015Article
- The Day-Hospital of the University Hospital, Bobo Dioulasso: An Example of Optimized HIV Management in Southern Burkina Faso.PloS one · 2015Observational
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
objectiveTo determine whether earlier initiation of antiretroviral therapy (ART) is associated with better economic outcomes.
designProspective cohort study of HIV-positive patients on ART in rural Uganda.
methodsPatients initiating ART at a regional referral clinic in Uganda were enrolled in the Uganda AIDS Rural Treatment Outcomes study starting in 2005. Data on labor force participation and asset ownership were collected on a yearly basis, and CD4 cell counts were collected at pre-ART baseline. We fitted multivariable regression models to assess whether economic outcomes at baseline and in the 6 years following ART initiation varied by baseline CD4 cell count.
resultsFive hundred and five individuals, followed up to 6 years, formed the estimation sample. Participants initiating ART at CD4 cell count at least 200 cells/μl were 13 percentage points more likely to be working at baseline (P < 0.01, 95% confidence interval 0.06-0.21) than those initiating below this threshold. Those in the latter group achieved similar labor force participation rates within 1 year of initiating ART (P < 0.01 on the time indicators). Both groups had similar asset scores at baseline and demonstrated similar increases in asset scores over the 6 years of follow-up.
conclusionART helps participants initiating therapy at CD4 cell count below 200 cells/μl rejoin the labor force, though the findings for participants initiating with higher CD4 cell counts suggests that pretreatment declines in labor supply may be prevented altogether with earlier therapy. Baseline similarities in asset scores for those with early and advanced disease suggest that mechanisms other than morbidity may help drive the relationship between HIV infection and economic outcomes.
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