ArticleGenetics in medicine : official journal of the American College of Medical Genetics2014
Horizon scanning for translational genomic research beyond bench to bedside.
Article in Genetics in medicine : official journal of the American College of Medical Genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- The expanding global genomics landscape: Converging priorities from national genomics programs.American journal of human genetics · 2025Review
- Availability and funding of clinical genomic sequencing globally.BMJ global health · 2021Review
- The Population Health OutcomEs aNd Information EXchange (PHOENIX) Program - A Transformative Approach to Reduce the Burden of Chronic Disease.Online journal of public health informatics · 2020Article
- Personalized Medicine Implementation with Non-traditional Data Sources: A Conceptual Framework and Survey of the Literature.Yearbook of medical informatics · 2019Review
- The current state of funded NIH grants in implementation science in genomic medicine: a portfolio analysis.Genetics in medicine : official journal of the American College of Medical Genetics · 2019Article
- A logic model for precision medicine implementation informed by stakeholder views and implementation science.Genetics in medicine : official journal of the American College of Medical Genetics · 2019Article
- HLBS-PopOmics: an online knowledge base to accelerate dissemination and implementation of research advances in population genomics to reduce the burden of heart, lung, blood, and sleep disorders.Genetics in medicine : official journal of the American College of Medical Genetics · 2019Review
- Using deep learning to identify translational research in genomic medicine beyond bench to bedside.Database : the journal of biological databases and curation · 2019Article
- Tracking human genes along the translational continuum.NPJ genomic medicine · 2019Article
- The current state of implementation science in genomic medicine: opportunities for improvement.Genetics in medicine : official journal of the American College of Medical Genetics · 2017Review
- Editorial. Life Sciences in an Integrated Curriculum: Starting the Conversation.MedEdPublish (2016) · 2017Article
- A knowledge base for tracking the impact of genomics on population health.Genetics in medicine : official journal of the American College of Medical Genetics · 2016Article
- Scanning the human genome and the horizon: the potential and pitfalls of pharmacogenetics and stratified medicine.The British journal of general practice : the journal of the Royal College of General Practitioners · 2015Article
- Public awareness of genetic nondiscrimination laws in four states and perceived importance of life insurance protections.Journal of genetic counseling · 2015Article
- Mapping the Ethics of Translational Genomics: Situating Return of Results and Navigating the Research-Clinical Divide.The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics · 2015Article
- Genomics in Public Health: Perspective from the Office of Public Health Genomics at the Centers for Disease Control and Prevention (CDC).Healthcare (Basel, Switzerland) · 2015Article
- Evidence synthesis and guideline development in genomic medicine: current status and future prospects.Genetics in medicine : official journal of the American College of Medical Genetics · 2015Article
- What is translational genomics? An expanded research agenda for improving individual and population health.Applied & translational genomics · 2014Article
- Medicine. Big data meets public health.Science (New York, N.Y.) · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
purposeThe dizzying pace of genomic discoveries is leading to an increasing number of clinical applications. In this report, we provide a method for horizon scanning and 1 year data on translational research beyond bench to bedside to assess the validity, utility, implementation, and outcomes of such applications.
methodsWe compiled cross-sectional results of ongoing horizon scanning of translational genomic research, conducted between 16 May 2012 and 15 May 2013, based on a weekly, systematic query of PubMed. A set of 505 beyond bench to bedside articles were collected and classified, including 312 original research articles; 123 systematic and other reviews; 38 clinical guidelines, policies, and recommendations; and 32 articles describing tools, decision support, and educational materials.
resultsMost articles (62%) addressed a specific genomic test or other health application; almost half of these (n = 180) were related to cancer. We estimate that these publications account for 0.5% of reported human genomics and genetics research during the same time.
conclusionThese data provide baseline information to track the evolving knowledge base and gaps in genomic medicine. Continuous horizon scanning of the translational genomics literature is crucial for an evidence-based translation of genomics discoveries into improved health care and disease prevention.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.