ArticleJournal of ovarian research2014
Seasonal changes in expression of nerve growth factor and its receptors TrkA and p75 in the ovary of wild ground squirrel (Citellus dauricus Brandt).
Article in Journal of ovarian research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Modulation of Female Reproductive Functions through Nerve Growth Factor: A Systematic Review.Expert reviews in molecular medicine · 2026Pooled it
- Seasonal patterns of prolactin, prolactin receptor, and STAT5 expression in the ovaries of wild ground squirrels (<em>Citellus dauricus</em> Brandt).European journal of histochemistry : EJH · 2023Article
- Clinical observation of recombinant human nerve growth factor in the treatment of neurotrophic keratitis.International journal of ophthalmology · 2023Article
- Seasonal Change in Adiponectin Associated with Ovarian Morphology and Function in Wild Ground Squirrels (International journal of molecular sciences · 2022Article
- Expression of Nerve Growth Factor and Its Receptor TrkA in the Reproductive System of Adult Zebrafish.Veterinary sciences · 2022Article
- Seasonal Expression of NGF and Its Cognate Receptors in the Ovaries of Grey Squirrels (Animals : an open access journal from MDPI · 2020Article
- β-NGF Stimulates Steroidogenic Enzyme andFrontiers in veterinary science · 2020Article
- Seasonal expressions of androgen receptor, estrogen receptors and cytochrome P450 aromatase in the uteri of the wild Daurian ground squirrels (Spermophilus dauricus).European journal of histochemistry : EJH · 2018Article
- Expression and Functional Analysis of the BCL2-Associated Agonist of Cell Death (Frontiers in endocrinology · 2018Article
- Testicular expression of NGF, TrkA and p75 during seasonal spermatogenesis of the wild ground squirrel (Citellus dauricus Brandt).European journal of histochemistry : EJH · 2015Article
- Immunolocalization of NGF and its receptors in ovarian surface epithelium of the wild ground squirrel during the breeding and nonbreeding seasons.European journal of histochemistry : EJH · 2014Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to investigate the presence of nerve growth factor (NGF) and its receptors tyrosine kinase A (TrkA) and p75 in the ovaries of the wild ground squirrels during the breeding and nonbreeding seasons. In the breeding period, NGF, TrkA and p75 were immunolocalized in granulosa cells, thecal cells, interstitial cells and luteal cells whereas in the nonbreeding period, both of them were detected only in granulosa cells, thecal cells and interstitial cells. Stronger immunostaining of NGF, TrkA and p75 were observed in granulosa cells, thecal cells and interstitial cells in the breeding season compared to the nonbreeding season. Corresponding for the immunohistochemical results, immunoreactivities of NGF and its two receptors were greater in the ovaries of the breeding season then decreased to a relatively low level in the nonbreeding season. The mean mRNA levels of NGF, TrkA and p75 were significantly higher in the breeding season than in the nonbreeding season. In addition, plasma gonadotropins, estradiol-17β and progesterone concentrations were significantly higher in the breeding season than in the nonbreeding season, suggesting that the expression patterns of NGF, and TrkA and p75 were correlated with changes in plasma gonadotropins, estradiol-17β and progesterone concentrations. These results indicated that NGF and its receptors, TrkA and p75 may be involved in the regulation of seasonal changes in the ovarian functions of the wild ground squirrel.
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