ArticleBritish journal of pharmacology1987
Failure of the calcium channel activator, Bay K 8644, to increase the release of acetylcholine from nerve terminals in brain and diaphragm.
Article in British journal of pharmacology, 1987. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 18 citations in OpenAlex.
- Calcium channels involved in the inhibition of acetylcholine release by presynaptic muscarinic receptors in rat striatum.British journal of pharmacology · 1999Article
- Novel selective agonists and antagonists confirm neurokinin NK1 receptors in guinea-pig vas deferens.British journal of pharmacology · 1991Article
- Actions and interactions of dihydropyridines and ethanol on the rat sinus node.Cardiovascular drugs and therapy · 1989Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
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Abstract
The calcium channel activator Bay K 8644 did not increase the release of acetylcholine from rat brain cortex prisms incubated in the presence of 3 mmol l-1 or 25 mmol l-1 K+ nor from rat diaphragms incubated in the presence of 5 mmol l-1 or 25 mmol l-1 K+. It also did not influence the release of acetylcholine from cortex prisms incubated in the presence of 25 mmol l-1 K+ and of lowered concentrations of Ca2+ ions. It is concluded that the voltage-dependent Ca2+ channels in the nerve terminals, responsible for the depolarization-induced influx of Ca2+ ions into the nerve terminals and thus for the depolarization-evoked release of acetylcholine from the nerve terminals, are different from the voltage-dependent Ca2+ channels in the heart and smooth muscle cells.
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