ArticleJournal of the American Geriatrics Society2014
Prolonged mechanical ventilation in 540 seriously ill older adults: effects of increasing age on clinical outcomes and survival.
Article in Journal of the American Geriatrics Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 56 citations in OpenAlex.
- Trial
- Effect of remimazolam besylate on elderly patients with mechanical ventilation: a single-center randomized controlled study.BMC anesthesiology · 2025Trial
- Surgical Stabilization of Rib Fractures in Geriatric Trauma Patients: A National Trauma Data Bank Review.Journal of the American Geriatrics Society · 2026Article
- Factors Influencing Mechanical Ventilation and Inpatient Palliative Care Utilization in Patients With Chronic Obstructive Pulmonary Disease.Journal of multidisciplinary healthcare · 2025Article
- Geriatric rehabilitation center outcomes after successful weaning from extremely prolonged mechanical ventilation in older adults.Croatian medical journal · 2024Article
- The Age of Older Patients Requiring Prolonged Mechanical Ventilation Is Not the Sole Determinant of Their Long-Term Survival.Medicina (Kaunas, Lithuania) · 2024Article
- Estimation of the optimal time needed for weaning of Intensive Care Unit tracheostomized patients on mechanical ventilation. A prospective observational study.Acta bio-medica : Atenei Parmensis · 2023Observational
- Prognosis of Chronically Ventilated Patients in a Long-Term Ventilation Facility: Association with Age, Consciousness and Cognitive State.Journal of intensive care medicine · 2022Article
- Gender Differences in Prolonged Mechanical Ventilation Patients - A Retrospective Observational Study.International journal of general medicine · 2022Article
- Article
- Age, Frailty, Resuscitation and Intensive Care: With Reference to COVID-19.Geriatrics (Basel, Switzerland) · 2021Article
- The Long-Term Survival of Successfully Weaned Prolonged Mechanical Ventilation Patients.International journal of general medicine · 2021Article
- Predictors of prolonged mechanical ventilation identified at an emergency visit for elderly people: A retrospective cohort study.Medicine · 2020Article
- Endotracheal Tube Duration in Elderly Patients after the Coronary Artery Bypass Grafting Surgery.Tanaffos · 2020Article
- Article
- Article
- Article
- Prognosis After Emergency Department Intubation to Inform Shared Decision-Making.Journal of the American Geriatrics Society · 2018Article
- Index to Predict In-hospital Mortality in Older Adults after Non-traumatic Emergency Department Intubations.The western journal of emergency medicine · 2017Article
- Clinical Momentum in the Intensive Care Unit. A Latent Contributor to Unwanted Care.Annals of the American Thoracic Society · 2017Article
Corrections and comments
- Commented on by
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate effects of older age, comorbidities, and physiological measures on outcomes of elderly adults requiring prolonged mechanical ventilation (PMV).
designRetrospective cohort study.
settingPublic long-term acute care hospital (LTACH) with an active program for ventilator weaning from PMV.
participantsChronically seriously ill individuals with PMV aged 65 and older divided into six cohorts (65-69, 70-74, 75-79, 80-84, 85-89, ≥ 90) for comparative purposes (n = 540). MEASUREMENTS: Main outcomes were weaning criteria met, weaning success, discharge dispositions, and long-term survival. Other outcomes included weaning duration, LTACH days, discharge physical function, tracheostomy decannulation, and relapses to ventilator support. Weaning success was defined as 4 weeks or longer entirely free from mechanical ventilator support.
resultsThe main finding from age cohort comparisons was that the likelihood of meeting weaning criteria (P = .001) and subsequent successful weaning (P = .002) decreased with age. Best predictors for weaning success in multivariable analysis were lower comorbidity burden (P < .001) and less-severe illness (P = .001). Other clinically important predictors were more-normal values in the respiratory physiology measures of rapid shallow breathing (P = .001) and static compliance (P = .003). Successful weaning was also associated with a 62% lower risk of death (P < .001).
conclusionAlthough meeting weaning criteria and being successfully weaned decreased with increasing age, age was not the dominant factor in predicting outcomes. More importantly, individuals with PMV with better respiratory physiology and lower comorbidity burdens were more likely to be weaned and have longer survival, no matter their age.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.