Evidence map›Paper›PMID 24404558›Full record

ArticleJournal of cardiovascular disease2014

The Impact of Myocardial Infarction vs. Pneumonia on Outcome in Acute Ischemic Stroke.

Tiffany L Mathias, Karen C Albright, Amelia K Boehme, Dominique Monlezun, Alexander J George, Erica Jones, T Mark Beasley, Sheryl Martin-Schild

Open access · greenAbstract read
In one paragraph

Article in Journal of cardiovascular disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Tiffany L MathiasStroke Program, Department of Neurology, Tulane University Hospital, New Orleans, LA 70112 (TLM, DM, AJG, EJ, SMS); Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35249 (KCA, AKB); Health Services and Outcomes Research Center for Outcome and Effectiveness Research and Education (COERE) (KCA); Center of Excellence in Comparative Effectiveness Research for Eliminating Disparities (CERED) Minority Health & Health Disparities Research Center (MHRC) (KCA); Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35249 (TMB).
Karen C AlbrightStroke Program, Department of Neurology, Tulane University Hospital, New Orleans, LA 70112 (TLM, DM, AJG, EJ, SMS); Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35249 (KCA, AKB); Health Services and Outcomes Research Center for Outcome and Effectiveness Research and Education (COERE) (KCA); Center of Excellence in Comparative Effectiveness Research for Eliminating Disparities (CERED) Minority Health & Health Disparities Research Center (MHRC) (KCA); Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35249 (TMB).
Amelia K BoehmeStroke Program, Department of Neurology, Tulane University Hospital, New Orleans, LA 70112 (TLM, DM, AJG, EJ, SMS); Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35249 (KCA, AKB); Health Services and Outcomes Research Center for Outcome and Effectiveness Research and Education (COERE) (KCA); Center of Excellence in Comparative Effectiveness Research for Eliminating Disparities (CERED) Minority Health & Health Disparities Research Center (MHRC) (KCA); Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35249 (TMB).
Dominique MonlezunStroke Program, Department of Neurology, Tulane University Hospital, New Orleans, LA 70112 (TLM, DM, AJG, EJ, SMS); Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35249 (KCA, AKB); Health Services and Outcomes Research Center for Outcome and Effectiveness Research and Education (COERE) (KCA); Center of Excellence in Comparative Effectiveness Research for Eliminating Disparities (CERED) Minority Health & Health Disparities Research Center (MHRC) (KCA); Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35249 (TMB).
Alexander J GeorgeStroke Program, Department of Neurology, Tulane University Hospital, New Orleans, LA 70112 (TLM, DM, AJG, EJ, SMS); Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35249 (KCA, AKB); Health Services and Outcomes Research Center for Outcome and Effectiveness Research and Education (COERE) (KCA); Center of Excellence in Comparative Effectiveness Research for Eliminating Disparities (CERED) Minority Health & Health Disparities Research Center (MHRC) (KCA); Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35249 (TMB).
Erica JonesStroke Program, Department of Neurology, Tulane University Hospital, New Orleans, LA 70112 (TLM, DM, AJG, EJ, SMS); Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35249 (KCA, AKB); Health Services and Outcomes Research Center for Outcome and Effectiveness Research and Education (COERE) (KCA); Center of Excellence in Comparative Effectiveness Research for Eliminating Disparities (CERED) Minority Health & Health Disparities Research Center (MHRC) (KCA); Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35249 (TMB).
T Mark BeasleyStroke Program, Department of Neurology, Tulane University Hospital, New Orleans, LA 70112 (TLM, DM, AJG, EJ, SMS); Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35249 (KCA, AKB); Health Services and Outcomes Research Center for Outcome and Effectiveness Research and Education (COERE) (KCA); Center of Excellence in Comparative Effectiveness Research for Eliminating Disparities (CERED) Minority Health & Health Disparities Research Center (MHRC) (KCA); Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35249 (TMB).
Sheryl Martin-SchildStroke Program, Department of Neurology, Tulane University Hospital, New Orleans, LA 70112 (TLM, DM, AJG, EJ, SMS); Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35249 (KCA, AKB); Health Services and Outcomes Research Center for Outcome and Effectiveness Research and Education (COERE) (KCA); Center of Excellence in Comparative Effectiveness Research for Eliminating Disparities (CERED) Minority Health & Health Disparities Research Center (MHRC) (KCA); Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35249 (TMB).
Tulane University · US

Funding

RESEARCH TRAINING COREP60MD000502 · NIMHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI FOUAD, MONA N. · 2003 to 2016
$16.2M
UAB Health Services Research (HSR) Training ProgramT32HS013852 · AHRQ · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEVITAN, EMILY B, MUGAVERO, MICHAEL J · 2003 to 2024
$8.0M
AHRQ HHS T32 HS013852NIMHD NIH HHS P60 MD000502PHS HHS HS013852-07
6 · The paper itself

Abstract

The aim of this study was to examine the association between MI and PNA in the setting of acute ischemic stroke and patient outcome. Eligible patients were identified from a prospectively collected stroke registry and included if transthoracic echocardiography (TTE) was performed during their inpatient stay. 426 patients met inclusion criteria (mean age 64, 73% Black, 48% female). Twenty-one patients (4.9%) experienced an MI. Patients who later suffered a MI initially presented with more severe strokes (median NIHSS 7 vs. 5, p=0.014). More patients in the MI group experienced pneumonia (26% vs. 9%, p=0.004). After adjusting for age, baseline glucose and NIHSS, the odds of in-hospital mortality for patients with MI was 3 times that of those without MI (OR 3.2 95% CI 1.1-9.7, p=0.036). When adjustment was made for pneumonia, age, baseline glucose and NIHSS, MI was no longer significantly related to in-hospital mortality (OR 2.5 95% CI 0.8-8.2, p=0.131). In our sample, while MI was significantly associated with in-hospital mortality, this association was attenuated after adjusting for presence of pneumonia. Our findings raise the question as to whether the prevention of pneumonia could improve in-hospital mortality among patients who experience MI in the setting of ischemic stroke.

Indexed as

in-hospital mortalityischemic strokemyocardial infarction

Identifiers

PMID24404558
PMCPMC3882195
OpenAlexW2187981929

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.