Evidence map›Paper›PMID 24404075›Full record

ArticleBiomicrofluidics2013

Inducing self-rotation of cells with natural and artificial melanin in a linearly polarized alternating current electric field.

Mengxing Ouyang, Wing Ki Cheung, Wenfeng Liang, John D Mai, Wing Keung Liu, Wen Jung Li

Open access · bronzeAbstract read
In one paragraph

Article in Biomicrofluidics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Mengxing OuyangDepartment of Mechanical and Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong.
Wing Ki CheungSchool of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, N. T., Hong Kong.
Wenfeng LiangState Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang 110016, China.
John D MaiDepartment of Mechanical and Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong.
Wing Keung LiuSchool of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, N. T., Hong Kong.
Wen Jung LiDepartment of Mechanical and Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong ; State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang 110016, China.
Chinese University of Hong Kong · CNCity University of Hong Kong · HKChinese Academy of Sciences · CNShenyang Institute of Automation · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The phenomenon of self-rotation observed in naturally and artificially pigmented cells under an applied linearly polarized alternating current (non-rotating) electrical field has been investigated. The repeatable and controllable rotation speeds of the cells were quantified and their dependence on dielectrophoretic parameters such as frequency, voltage, and waveform was studied. Moreover, the rotation behavior of the pigmented cells with different melanin content was compared to quantify the correlation between self-rotation and the presence of melanin. Most importantly, macrophages, which did not originally rotate in the applied non-rotating electric field, began to exhibit self-rotation that was very similar to that of the pigmented cells, after ingesting foreign particles (e.g., synthetic melanin or latex beads). We envision the discovery presented in this paper will enable the development of a rapid, non-intrusive, and automated process to obtain the electrical conductivities and permittivities of cellular membrane and cytoplasm in the near future.

Identifiers

PMID24404075
PMCPMC3799643
OpenAlexW2021635244

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.