ArticleBiomicrofluidics2013
Rare cell isolation and profiling on a hybrid magnetic/size-sorting chip.
Article in Biomicrofluidics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Ascites analysis by a microfluidic chip allows tumor-cell profiling.Proceedings of the National Academy of Sciences of the United States of America · 2013Trial
- Clog-free high-throughput microfluidic cell isolation with multifunctional microposts.Scientific reports · 2021Article
- Self-Assembled Permanent Micro-Magnets in a Polymer-Based Microfluidic Device for Magnetic Cell Sorting.Cells · 2021Article
- Immunomagnetic separation of circulating tumor cells with microfluidic chips and their clinical applications.Biomicrofluidics · 2020Review
- Magnetically driven microfluidics for isolation of circulating tumor cells.Cancer medicine · 2020Review
- Development and Clinical Prospects of Techniques to Separate Circulating Tumor Cells from Peripheral Blood.Cancer management and research · 2020Review
- An intravascular magnetic wire for the high-throughput retrieval of circulating tumour cells in vivo.Nature biomedical engineering · 2018Article
- Magnetic Force-Based Microfluidic Techniques for Cellular and Tissue Bioengineering.Frontiers in bioengineering and biotechnology · 2018Review
- Highly-sensitive capture of circulating tumor cells using micro-ellipse filters.Scientific reports · 2017Article
- Design of a Microfluidic Chip for Magnetic-Activated Sorting of One-Bead-One-Compound Libraries.ACS combinatorial science · 2016Article
- Recent Developments in Magnetic Diagnostic Systems.Chemical reviews · 2015Review
- Digital Microfluidics for Manipulation and Analysis of a Single Cell.International journal of molecular sciences · 2015Review
- Simultaneous diamagnetic and magnetic particle trapping in ferrofluid microflows via a single permanent magnet.Biomicrofluidics · 2015Article
- Fundamentals and application of magnetic particles in cell isolation and enrichment: a review.Reports on progress in physics. Physical Society (Great Britain) · 2015Review
- Miniaturized, multiplexed readout of droplet-based microfluidic assays using time-domain modulation.Lab on a chip · 2014Article
- Magnetophoretic manipulation in microsystem using carbonyl iron-polydimethylsiloxane microstructures.Biomicrofluidics · 2014Article
- Modulation of rotation-induced lift force for cell filtration in a low aspect ratio microchannel.Biomicrofluidics · 2014Article
- Track-etched magnetic micropores for immunomagnetic isolation of pathogens.Advanced healthcare materials · 2014Article
- Cancer cell profiling by barcoding allows multiplexed protein analysis in fine-needle aspirates.Science translational medicine · 2014Article
- Laser micromachined hybrid open/paper microfluidic chips.Biomicrofluidics · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
We present a hybrid magnetic/size-sorting (HMSS) chip for isolation and molecular analyses of circulating tumor cells (CTCs). The chip employs both negative and positive cell selection in order to provide high throughput, unbiased CTC enrichment. Specifically, the system utilizes a self-assembled magnet to generate high magnetic forces and a weir-style structure for cell sorting. The resulting device thus can perform multiple functions, including magnetic depletion, size-selective cell capture, and on-chip molecular staining. With such capacities, the HMSS device allowed one-step CTC isolation and single cell detection from whole blood, tested with spiked cancer cells. The system further facilitated the study of individual CTCs for heterogeneity in molecular marker expression.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.