ArticleBiomicrofluidics2013
Viscoelasticity of blood and viscoelastic blood analogues for use in polydymethylsiloxane in vitro models of the circulatory system.
Article in Biomicrofluidics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Trial
- Developing a non-invasive diagnostic framework for the fractional flow reserve quantification in left coronary arteries: validation with patient cases.Frontiers in physiology · 2026Article
- Predicting cardiac frequencies in mammals.Scientific reports · 2025Article
- Progress on a Novel, 3D-Printable Heart Valve Prosthesis.Polymers · 2023Article
- Quantification of Blood Viscoelasticity under Microcapillary Blood Flow.Micromachines · 2023Article
- Evolution of focused streams for viscoelastic flow in spiral microchannels.Microsystems & nanoengineering · 2023Article
- Simulation of Mechanical Heart Valve Dysfunction and the Non-Newtonian Blood Model Approach.Applied bionics and biomechanics · 2022Review
- Passive and Active Microrheology for Biomedical Systems.Frontiers in bioengineering and biotechnology · 2022Review
- Extensional Magnetorheology of Viscoelastic Human Blood Analogues Loaded with Magnetic Particles.Materials (Basel, Switzerland) · 2021Article
- Blood Particulate Analogue Fluids: A Review.Materials (Basel, Switzerland) · 2021Review
- Hemodynamic analysis for stenosis microfluidic model of thrombosis with refined computational fluid dynamics simulation.Scientific reports · 2021Article
- Visualization and Measurements of Blood Cells Flowing in Microfluidic Systems and Blood Rheology: A Personalized Medicine Perspective.Journal of personalized medicine · 2020Review
- Estimation Methods for Viscosity, Flow Rate and Pressure from Pump-Motor Assembly Parameters.Sensors (Basel, Switzerland) · 2020Article
- Blood Viscoelasticity Measurement Using Interface Variations in Coflowing Streams under Pulsatile Blood Flows.Micromachines · 2020Article
- Optical coherence tomography for evaluating capillary waves in blood and plasma.Biomedical optics express · 2020Article
- Effects of Ionic Strength on Lateral Particle Migration in Shear-Thinning Xanthan Gum Solutions.Micromachines · 2019Article
- Microfluidic Deformability Study of an Innovative Blood Analogue Fluid Based on Giant Unilamellar Vesicles.Journal of functional biomaterials · 2018Article
- Formation of Blood Droplets: Influence of the Plasma Proteins.ACS omega · 2018Article
- Flow-induced deformation in a microchannel with a non-Newtonian fluid.Biomicrofluidics · 2018Article
- Emergent behaviors in RBCs flows in micro-channels using digital particle image velocimetry.Microvascular research · 2018Article
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Authors and funding
5 authors.
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Abstract
The non-Newtonian properties of blood are of great importance since they are closely related with incident cardiovascular diseases. A good understanding of the hemodynamics through the main vessels of the human circulatory system is thus fundamental in the detection and especially in the treatment of these diseases. Very often such studies take place in vitro for convenience and better flow control and these generally require blood analogue solutions that not only adequately mimic the viscoelastic properties of blood but also minimize undesirable optical distortions arising from vessel curvature that could interfere in flow visualizations or particle image velocimetry measurements. In this work, we present the viscoelastic moduli of whole human blood obtained by means of passive microrheology experiments. These results and existing shear and extensional rheological data for whole human blood in the literature enabled us to develop solutions with rheological behavior analogous to real whole blood and with a refractive index suited for PDMS (polydymethylsiloxane) micro- and milli-channels. In addition, these blood analogues can be modified in order to obtain a larger range of refractive indices from 1.38 to 1.43 to match the refractive index of several materials other than PDMS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.