ReviewBiomicrofluidics2013
Hydrodynamic mechanisms of cell and particle trapping in microfluidics.
Review in Biomicrofluidics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
99 citing papers in PubMed.
- A Review of the Application of Compliance Phenomenon in Particle Separation Within Microfluidic Systems.Micromachines · 2025Review
- Sheathless Elasto-Inertial Focusing of Sub-25 Nm Particles in Straight Microchannels.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Surface Acoustic Wave-Based Microfluidic Device for Microparticles Manipulation: Effects of Microchannel Elasticity on the Device Performance.Micromachines · 2023Article
- Low-cost acoustic force trap in a microfluidic channel.HardwareX · 2023Article
- Direct separation and enumeration of CTCs in viscous blood based on co-flow microchannel with tunable shear rate: a proof-of-principle study.Analytical and bioanalytical chemistry · 2022Article
- Recent advances in acoustic microfluidics and its exemplary applications.Biomicrofluidics · 2022Review
- Lab-on-a-Chip Platforms for Airborne Particulate Matter Applications: A Review of Current Perspectives.Biosensors · 2022Review
- Microfluidics geometries involved in effective blood plasma separation.Microfluidics and nanofluidics · 2022Review
- Strong confinement of active microalgae leads to inversion of vortex flow and enhanced mixing.eLife · 2021Article
- Applications of Microfluidics in Liquid Crystal-Based Biosensors.Biosensors · 2021Review
- Clog-free high-throughput microfluidic cell isolation with multifunctional microposts.Scientific reports · 2021Article
- Integration of a Dielectrophoretic Tapered Aluminum Microelectrode Array with a Flow Focusing Technique.Sensors (Basel, Switzerland) · 2021Article
- An easy-to-operate method for single-cell isolation and retrieval using a microfluidic static droplet array.Mikrochimica acta · 2021Article
- Microfluidics for Peptidomics, Proteomics, and Cell Analysis.Nanomaterials (Basel, Switzerland) · 2021Review
- The influence of cell elastic modulus on inertial positions in Poiseuille microflows.Biophysical journal · 2021Article
- Inertial cell sorting of microparticle-laden flows: An innovative OpenFOAM-based arbitrary Lagrangian-Eulerian numerical approach.Biomicrofluidics · 2021Article
- Three step flow focusing enables image-based discrimination and sorting of late stage 1 Haematococcus pluvialis cells.PloS one · 2021Article
- A density-based threshold model for evaluating the separation of particles in heterogeneous mixtures with curvilinear microfluidic channels.Scientific reports · 2020Article
- Analytical Guidelines for Designing Curvature-Induced Dielectrophoretic Particle Manipulation Systems.Micromachines · 2020Article
- Effect of elastic modulus on inertial displacement of cell-like particles in microchannels.Biomicrofluidics · 2020Article
39 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Focusing and sorting cells and particles utilizing microfluidic phenomena have been flourishing areas of development in recent years. These processes are largely beneficial in biomedical applications and fundamental studies of cell biology as they provide cost-effective and point-of-care miniaturized diagnostic devices and rare cell enrichment techniques. Due to inherent problems of isolation methods based on the biomarkers and antigens, separation approaches exploiting physical characteristics of cells of interest, such as size, deformability, and electric and magnetic properties, have gained currency in many medical assays. Here, we present an overview of the cell/particle sorting techniques by harnessing intrinsic hydrodynamic effects in microchannels. Our emphasis is on the underlying fluid dynamical mechanisms causing cross stream migration of objects in shear and vortical flows. We also highlight the advantages and drawbacks of each method in terms of throughput, separation efficiency, and cell viability. Finally, we discuss the future research areas for extending the scope of hydrodynamic mechanisms and exploring new physical directions for microfluidic applications.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.