ArticleBiomicrofluidics2013
Label-free isolation of circulating tumor cells in microfluidic devices: Current research and perspectives.
Article in Biomicrofluidics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04638868 (A Head-to-head Comparison of a Novel Silicon Microsieve Device Against a Cell Surface Marker-based Platform for the Isolation of Portal Vein Circulating Tumor Cells in Pancreatic Cancer), which is not on this map. Cited by 37 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Head-to-head Comparison of a Novel Silicon Microsieve Device Against a Cell Surface Marker-based Platform for the Isolation of Portal Vein Circulating Tumor Cells in Pancreatic Cancer
Who cites it
37 citing papers in PubMed.
- Microfluidic device (ExoChip) for on-chip isolation, quantification and characterization of circulating exosomes.Lab on a chip · 2014Trial
- Diagnostic efficacy of circulating tumor cell in clinically significant prostate cancer.Scientific reports · 2026Article
- Liquid Biopsy: A Game Changer for Type 2 Diabetes.International journal of molecular sciences · 2024Review
- Microfluidics engineering towards personalized oncology-a review.In vitro models · 2023Review
- Enhanced prognostic value of combined circulating tumor cells and serum carcinoembryonic antigen in patients with colorectal cancer.Journal of the Chinese Medical Association : JCMA · 2023Article
- MiSelect R System: the validation of a new detection system of CTCs and their correlation with prognosis in non-metastatic CRC patients.Scientific reports · 2023Article
- Review
- Review
- Sequential Ensemble-Decision Aliquot Ranking Isolation and FluorescenceAnalytical chemistry · 2021Article
- Scalable Signature-Based Molecular Diagnostics Through On-chip Biomarker Profiling Coupled with Machine Learning.Annals of biomedical engineering · 2020Review
- Recent advances in microfluidic methods in cancer liquid biopsy.Biomicrofluidics · 2019Review
- Biophysical Insights on the Enrichment of Cancer Cells from Whole Blood by (Affinity) Filtration.Scientific reports · 2019Article
- Emerging Technologies for Cancer Research: Towards Personalized Medicine with Microfluidic Platforms and 3D Tumor Models.Current medicinal chemistry · 2018Review
- Dielectrophoresis-based microfluidic platforms for cancer diagnostics.Biomicrofluidics · 2018Review
- An integrated microfluidic device for rapid and high-sensitivity analysis of circulating tumor cells.Scientific reports · 2017Article
- Multi-Phenotypic subtyping of circulating tumor cells using sequential fluorescent quenching and restaining.Scientific reports · 2016Article
- The Role of Surface Receptor Density in Surface-Initiated Polymerizations for Cancer Cell Isolation.Langmuir : the ACS journal of surfaces and colloids · 2016Article
- Investigation of particle inertial migration in high particle concentration suspension flow by multi-electrodes sensing and Eulerian-Lagrangian simulation in a square microchannel.Biomicrofluidics · 2016Article
- Ultra-fast, label-free isolation of circulating tumor cells from blood using spiral microfluidics.Nature protocols · 2016Article
- Precision Microfilters as an all in one System for Multiplex Analysis of Circulating Tumor Cells.RSC advances · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review will cover the recent advances in label-free approaches to isolate and manipulate circulating tumor cells (CTCs). In essence, label-free approaches do not rely on antibodies or biological markers for labeling the cells of interest, but enrich them using the differential physical properties intrinsic to cancer and blood cells. We will discuss technologies that isolate cells based on their biomechanical and electrical properties. Label-free approaches to analyze CTCs have been recently invoked as a valid alternative to "marker-based" techniques, because classical epithelial and tumor markers are lost on some CTC populations and there is no comprehensive phenotypic definition for CTCs. We will highlight the advantages and drawbacks of these technologies and the status on their implementation in the clinics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.