Evidence map›Paper›PMID 24403984›Full record

ArticleBiomicrofluidics2013

An integrated microfluidic device for rapid serodiagnosis of amebiasis.

Wang Zhao, Li Zhang, Wenwen Jing, Sixiu Liu, Hiroshi Tachibana, Xunjia Cheng, Guodong Sui

Open access · bronzeAbstract read
In one paragraph

Article in Biomicrofluidics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Wang ZhaoDepartment of Environmental Science and Engineering, Fudan University, 220 Handan Road, Shanghai 200433, People's Republic of China.
Li ZhangDepartment of Medical Microbiology and Parasitology, Medical Centre of Fudan University, Shanghai, 200032, People's Republic of China.
Wenwen JingDepartment of Environmental Science and Engineering, Fudan University, 220 Handan Road, Shanghai 200433, People's Republic of China.
Sixiu LiuDepartment of Environmental Science and Engineering, Fudan University, 220 Handan Road, Shanghai 200433, People's Republic of China.
Hiroshi TachibanaDepartment of Infectious Diseases, School of Medicine, Tokai University, Isehara, Kanagawa 259-1193, Japan.
Xunjia ChengDepartment of Medical Microbiology and Parasitology, Medical Centre of Fudan University, Shanghai, 200032, People's Republic of China.
Guodong SuiDepartment of Environmental Science and Engineering, Fudan University, 220 Handan Road, Shanghai 200433, People's Republic of China.
Fudan University · CNTokai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A microfluidic device was successfully fabricated for the rapid serodiagnosis of amebiasis. A micro bead-based immunoassay was fabricated within integrated microfluidic chip to detect the antibody to Entamoeba histolytica in serum samples. In this assay, a recombinant fragment of C terminus of intermediate subunit of galactose and N-acetyl-D-galactosamine-inhibitable lectin of Entamoeba histolytica (C-Igl, aa 603-1088) has been utilized instead of the crude antigen. This device was validated with serum samples from patients with amebiasis and showed great sensitivity. The serodiagnosis can be completed within 20 min with 2 μl sample consumption. The device can be applied for the rapid and cheap diagnosis of other infectious disease, especially for the developing countries with very limited medical facilities.

Identifiers

PMID24403984
PMCPMC3592878
OpenAlexW1983979923

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.