Evidence map›Paper›PMID 24403725›Full record

ArticleJournal of modern optics2012

Dynamic intrinsic optical signal monitoring of electrically stimulated inner retinal neural response.

Yi-Chao Li, Jian-Min Luo, Rong-Wen Lu, Kai-Mao Liu, Alexander Miles Levy, Xin-Cheng Yao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of modern optics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Functional optical coherence tomography of retinal photoreceptors.Experimental biology and medicine (Maywood, N.J.) · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yi-Chao LiDepartment of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Jian-Min LuoDepartment of Ophthalmology and Visual Sciences, University of Nebraska Medical Center, Omaha, NE 68138, USA.
Rong-Wen LuDepartment of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Kai-Mao LiuDepartment of Biochemistry & Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Alexander Miles LevyDepartment of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Xin-Cheng YaoDepartment of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL 35294, USA ; Department of Vision Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

Funding

Multifocal Optical Coherence MicroscopeR21RR025788 · NCRR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI YAO, XINCHENG · 2009 to 2010
$517k
Angle-resolved polarization signal imaging of early receptor potentialR21EB012264 · NIBIB · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI YAO, XINCHENG · 2011 to 2012
$381k
NCRR NIH HHS R21 RR025788NIBIB NIH HHS R21 EB012264
6 · The paper itself

Abstract

Dynamic monitoring of stimulus-evoked inner neural response is important for functional validation of stimulation protocols of retinal prosthetic devices. In this paper, we demonstrate label-free intrinsic optical signal (IOS) imaging of electrically stimulated inner neural response in freshly isolated mouse retinas. While single-pulse stimulation evoked rapid IOS within 20 ms, pulse-train stimulation indicated that the fast IOS response can follow frequency stimulation up to at least 8 Hz. Fast IOS imaging promises a noninvasive method for high resolution examination of electrically evoked retinal response, without artifact contamination of electrical stimulus.

Indexed as

ganglion cellintrinsic optical signalretinal functionretinal prosthesis

Identifiers

PMID24403725
PMCPMC3882170

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.