Evidence map›Paper›PMID 24402841›Full record

ArticleMedicine, health care, and philosophy2014

The value and pitfalls of speculation about science and technology in bioethics: the case of cognitive enhancement.

Eric Racine, Tristana Martin Rubio, Jennifer Chandler, Cynthia Forlini, Jayne Lucke

Abstract read
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In one paragraph

Article in Medicine, health care, and philosophy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Article
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  5. Article
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  12. Neuroethics for Fantasyland or for the Clinic? The Limitations of Speculative Ethics.Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees · 2020
    Article
  13. Separating neuroethics from neurohype.Nature biotechnology · 2019
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. The methodological rigor of anticipatory bioethics.Medicine, health care, and philosophy · 2014
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eric RacineNeuroethics Research Unit, Institut de recherches cliniques de Montréal (IRCM), 110 Avenue des Pins Ouest, Montreal, QC, H2W lR7, Canada, eric.racine@ircm.qc.ca.
Tristana Martin Rubio
Jennifer Chandler
Cynthia Forlini
Jayne Lucke

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

In the debate on the ethics of the non-medical use of pharmaceuticals for cognitive performance enhancement in healthy individuals there is a clear division between those who view "cognitive enhancement" as ethically unproblematic and those who see such practices as fraught with ethical problems. Yet another, more subtle issue, relates to the relevance and quality of the contribution of scholarly bioethics to this debate. More specifically, how have various forms of speculation, anticipatory ethics, and methods to predict scientific trends and societal responses augmented or diminished this contribution? In this paper, we use the discussion of the ethics of cognitive enhancement to explore the positive and negative contribution of speculation in bioethics scholarship. First, we review and discuss how speculation has relied on different sets of assumptions regarding the non-medical use of stimulants, namely: (1) terminology and framing; (2) scientific aspects such as efficacy and safety; (3) estimates of prevalence and consequent normalization; and (4) the need for normative reflection and regulatory guidelines. Second, three methodological guideposts are proposed to alleviate some of the pitfalls of speculation: (1) acknowledge assumptions more explicitly and identify the value attributed to assumptions; (2) validate assumptions with interdisciplinary literature; and (3) adopt a broad perspective to promote more comprehensive reflection. We conclude that, through the examination of the controversy about cognitive enhancement, we can employ these methodological guideposts to enhance the value of contributions from bioethics and minimize potential epistemic and practical pitfalls in this case and perhaps in other areas of bioethical debate.

Indexed as

BioethicsCognitionBiomedical ResearchCentral Nervous System StimulantsHumansInterdisciplinary CommunicationScienceTechnologyCentral Nervous System Stimulants

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.