ReviewCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2014
Peripheral arterial calcification: prevalence, mechanism, detection, and clinical implications.
Review in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 241 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The REALITY Study: DiRectional AthErectomy + Drug-CoAted BaLloon to Treat Long, CalcifIed FemoropopliTeal ArterY Lesions
Clinical and Economic Outcome of Endovascular Therapies in Chronic Femoropopliteal Occlusive Disease With Severe Calcification (The Evolution Study): a Prospective, Multi-center，Observational Study
The THOR IDE Study
The PORTuguese Registry of Supera Supported Femoral-Fopliteal Revascularization (SupPORT Registry)
Evaluation of the Safety and Efficacy of the Chocolate Balloon Catheter in Percutaneous Transluminal Angioplasty (PTA) for Peripheral Arterial Disease (PAD): A Prospective, Multicenter, Single-Arm Observational Trial
Who cites it
241 citing papers in PubMed, 2 syntheses or guidelines pooled it, 579 citations in OpenAlex.
- Pooled it
- Quantification of arterial calcification in peripheral artery disease and its association with amputation and/or mortality: A systematic review.Vascular medicine (London, England) · 2025Pooled it
- Differences in major limb outcomes by indication for lower extremity endovascular revascularization in patients receiving hemodialysis.Heart and vessels · 2023Trial
- COMPARE: prospective, randomized, non-inferiority trial of high- vs. low-dose paclitaxel drug-coated balloons for femoropopliteal interventions.European heart journal · 2020Trial
- One-year results of drug-coated balloons for long and occlusive Femoropopliteal artery disease: a single-arm trial.BMC cardiovascular disorders · 2020Trial
- Femoral Arterial Calcification, Atherogenic Index of Plasma, and 1-Year Mortality After Hip Fracture: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Long-term outcomes of the "pave-and-crack" technique for severely calcified femoropopliteal chronic total occlusions.CVIR endovascular · 2026Article
- Feasibility and Early Results of Peripheral Intravascular Lithotripsy in Heavily Calcified Femoropopliteal Disease: Single-Center Experience.Acta Cardiologica Sinica · 2026Article
- A Prospective Evaluation of Optical Coherence Tomography in Below-the-Knee Endovascular Interventions.Journal of the Society for Cardiovascular Angiography & Interventions · 2026Article
- Low-Dose Versus High-Dose Drug-Coated Balloon After Jetstream Atherectomy for Severely Calcified Femoropopliteal Lesions: A Multicenter Registry Study.Cardiovascular and interventional radiology · 2026Article
- Pulsatile Intravascular Lithotripsy for Heavily Calcified Femoropopliteal Arterial Disease: First-in-Human Results from the POWER PAD I Feasibility Study.Journal of clinical medicine · 2026Article
- Review
- Sirolimus-eluting balloon for the treatment of peripheral artery disease: SUCCESS PTA real-world single-arm study.CVIR endovascular · 2026Article
- Contemporary outcomes of a DCB-based strategy with selective stent implantation for femoropopliteal artery lesions: results from the REAL-LEAD registry.CVIR endovascular · 2026Article
- Combined prognostic value of elevated lipoprotein(a) and severe calcification for limb outcomes after endovascular therapy.Heart and vessels · 2026Article
- Lesion Morphology and Technical Success in Diabetic vs. Non-Diabetic Patients with Chronic Limb-Threatening Ischemia Undergoing Endovascular Treatment: A Retrospective Single-Center Study.Medicina (Kaunas, Lithuania) · 2026Article
- Assessment of Recurrence Patterns and Treatment Strategies for Reintervention after Paclitaxel-Coated Balloon Angioplasty in Femoropopliteal Artery Diseases: Results of the ASTRA Study.Journal of atherosclerosis and thrombosis · 2026Article
- Impact of dual-pathway inhibitor therapy on outcomes after femoropopliteal in-stent occlusion.Cardiovascular intervention and therapeutics · 2026Article
- Predictors of target lesion restenosis after endovascular therapy for lower-extremity atherosclerotic peripheral artery disease: a real-world single center cohort.Journal of cardiothoracic surgery · 2026Article
- Comparative Mid-Term Outcomes of Endovascular Strategies for Femoropopliteal Lesions Extending to the Distal Popliteal Artery.Cardiovascular and interventional radiology · 2026Article
181 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vascular calcification (VC), particularly medial (Mönckeberg's medial sclerosis) arterial calcification, is common in patients with diabetes mellitus and chronic kidney disease and is associated with increased cardiovascular morbidity and mortality. Although, the underlying pathophysiological mechanisms and genetic pathways of VC are not fully known, hypocalcemia, hyperphosphatemia, and the suppression of parathyroid hormone activity are central to the development of vessel mineralization and, consequently, bone demineralization. In addition to preventive measures, such as the modification of atherosclerotic cardiovascular risk factors, current treatment strategies include the use of calcium-free phosphate binders, vitamin D analogs, and calcium mimetics that have shown promising results, albeit in small patient cohorts. The impact of intimal and medial VC on the safety and effectiveness of endovascular devices to treat symptomatic peripheral arterial disease (PAD) remains poorly defined. The absence of a generally accepted, validated vascular calcium grading scale hampers clinical progress in assessing the safety and utility of various endovascular devices (e.g., atherectomy) in treating calcified vessels. Accordingly, we propose the peripheral arterial calcium scoring system (PACSS) and a method for its clinical validation. A better understanding of the pathogenesis of vascular calcification and the development of optimal medical and endovascular treatment strategies are crucial as the population ages and presents with more chronic comorbidities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.