ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2014
The role of coupling strength and internal delay between compartments in shaping the bursting behavior of cortical neuron.
Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bursting is a typical firing behavior intrinsically existing in neurons from many brain regions, which has been thought to have functional roles in neuronal reliable signaling and synaptic plasticity. Meanwhile, many factors have been put forward to participate in the modulation of bursting behavior during the past decades. Here, in this research, the modulation of bursting behaviors was numerically investigated in a two-compartment model of cortical pyramidal neuron using the coupling strength and time delay between compartments as control parameters. By means of computer simulations, we showed that, for larger coupling strengths and smaller delays between the two compartments, a wide range of regular bursting can be observed, while too large coupling strengths and time delays would cause the model neuron to be quiescent. In addition, the dynamical firing range of regular spiking can be also obtained, which has two parts: one part corresponds to small coupling strengths irrespective of the values of time delay, while another part corresponds to larger coupling strengths and delays. These results suggested that coupling strength and internal time delay between the inner compartments possess potential roles in modulating the dynamical bursting behavior of neurons.
Indexed as
Identifiers
24402782What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.