Evidence map›Paper›PMID 24402174›Full record

ReviewMarine drugs2014

Astaxanthin: sources, extraction, stability, biological activities and its commercial applications--a review.

Ranga Rao Ambati, Siew Moi Phang, Sarada Ravi, Ravishankar Gokare Aswathanarayana

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Marine drugs, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 621 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
621citing papers in PubMed, 2 pooled it
30.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

621 citing papers in PubMed, 2 syntheses or guidelines pooled it, 1,881 citations in OpenAlex.

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561 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Ranga Rao AmbatiInstitute of Ocean and Earth Sciences, University of Malaya, Kuala Lumpur 50603, Malaysia. arangarao@um.edu.my.
Siew Moi PhangInstitute of Ocean and Earth Sciences, University of Malaya, Kuala Lumpur 50603, Malaysia. phang@um.edu.my.
Sarada RaviInstitute of Ocean and Earth Sciences, University of Malaya, Kuala Lumpur 50603, Malaysia. sarada_ravi@yahoo.com.
Ravishankar Gokare AswathanarayanaInstitute of Ocean and Earth Sciences, University of Malaya, Kuala Lumpur 50603, Malaysia. rgokare@yahoo.co.in.
University of Malaya · MYCouncil of Scientific and Industrial Research · INDr. Hari Singh Gour University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is currently much interest in biological active compounds derived from natural resources, especially compounds that can efficiently act on molecular targets, which are involved in various diseases. Astaxanthin (3,3'-dihydroxy-β, β'-carotene-4,4'-dione) is a xanthophyll carotenoid, contained in Haematococcus pluvialis, Chlorella zofingiensis, Chlorococcum, and Phaffia rhodozyma. It accumulates up to 3.8% on the dry weight basis in H. pluvialis. Our recent published data on astaxanthin extraction, analysis, stability studies, and its biological activities results were added to this review paper. Based on our results and current literature, astaxanthin showed potential biological activity in in vitro and in vivo models. These studies emphasize the influence of astaxanthin and its beneficial effects on the metabolism in animals and humans. Bioavailability of astaxanthin in animals was enhanced after feeding Haematococcus biomass as a source of astaxanthin. Astaxanthin, used as a nutritional supplement, antioxidant and anticancer agent, prevents diabetes, cardiovascular diseases, and neurodegenerative disorders, and also stimulates immunization. Astaxanthin products are used for commercial applications in the dosage forms as tablets, capsules, syrups, oils, soft gels, creams, biomass and granulated powders. Astaxanthin patent applications are available in food, feed and nutraceutical applications. The current review provides up-to-date information on astaxanthin sources, extraction, analysis, stability, biological activities, health benefits and special attention paid to its commercial applications.

Indexed as

AnimalsAnti-Inflammatory AgentsAntineoplastic AgentsAntioxidantsBiological AvailabilityBiological ProductsBiotechnologyCardiovascular AgentsDrug StabilityHumansHypoglycemic AgentsImmunologic FactorsMarine BiologyXanthophyllsAnti-Inflammatory AgentsAntineoplastic AgentsAntioxidantsastaxanthineBiological ProductsCardiovascular AgentsHypoglycemic AgentsImmunologic FactorsXanthophylls

Identifiers

PMID24402174
PMCPMC3917265
OpenAlexW1565527343

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.