Evidence map›Paper›PMID 24401081›Full record

ReviewMicrobial cell factories2014

Carbon source dependent promoters in yeasts.

Katrin Weinhandl, Margit Winkler, Anton Glieder, Andrea Camattari

Open access · goldAbstract readReview
In one paragraph

Review in Microbial cell factories, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 215 citations in OpenAlex.

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  14. Metabolic Engineering ofJournal of fungi (Basel, Switzerland) · 2024
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30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Katrin Weinhandl
Margit Winkler
Anton Glieder
Andrea CamattariInstitute of Molecular Biotechnology, Technical University Graz, Graz, Austria. andrea.camattari@tugraz.at.
Austrian Centre of Industrial Biotechnology (Austria) · ATGraz University of Technology · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Budding yeasts are important expression hosts for the production of recombinant proteins.The choice of the right promoter is a crucial point for efficient gene expression, as most regulations take place at the transcriptional level. A wide and constantly increasing range of inducible, derepressed and constitutive promoters have been applied for gene expression in yeasts in the past; their different behaviours were a reflection of the different needs of individual processes.Within this review we summarize the majority of the large available set of carbon source dependent promoters for protein expression in yeasts, either induced or derepressed by the particular carbon source provided. We examined the most common derepressed promoters for Saccharomyces cerevisiae and other yeasts, and described carbon source inducible promoters and promoters induced by non-sugar carbon sources. A special focus is given to promoters that are activated as soon as glucose is depleted, since such promoters can be very effective and offer an uncomplicated and scalable cultivation procedure.

Indexed as

Promoter Regions, GeneticAlcohol Dehydrogenasebeta-FructofuranosidaseCarbonMonocarboxylic Acid TransportersMonosaccharide Transport ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSymportersADH2 protein, S cerevisiaeAlcohol Dehydrogenasebeta-FructofuranosidaseCarbonJEN1 protein, S cerevisiaeMonocarboxylic Acid TransportersMonosaccharide Transport ProteinsSaccharomyces cerevisiae ProteinsSUC2 protein, S cerevisiaeSymporters

Identifiers

PMID24401081
PMCPMC3897899
OpenAlexW2122576785

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.