ReviewNature reviews. Neuroscience2013
Temporal fate specification and neural progenitor competence during development.
Review in Nature reviews. Neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 206 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
206 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Research Progress on Anti-Inflammatory Adipokine SFRP5-Mediated Lipid Metabolism and Its Potential Role in Neural Development.Immunity, inflammation and disease · 2026Pooled it
- Gene regulatory innovations from transposable elements in primate cerebellum development.Nature communications · 2026Article
- Delayed astrocyte development impairs Sema6a-Plxna2/4-mediated astrocyte-neuron crosstalk and causes depressive-like behavior.Nature communications · 2026Article
- The cellular basis of locomotor evolution: insights from larval insects.Current opinion in behavioral sciences · 2026Article
- Epilepsy-associated FOXJ3 variants link a transcriptional program of the PTEN-mTOR pathway to neuronal specification and cortical lamination.Nature communications · 2026Article
- Article
- Article
- Hormonal control of postmitotic neuronal identity.bioRxiv : the preprint server for biology · 2026Article
- Spatiotemporal analysis of genetic perturbations reveals a genetic cascade driving Tribolium gap gene initialization.Biology open · 2026Article
- The cis-regulatory logic integrating spatial and temporal patterning in the vertebrate neural tube.Developmental cell · 2025Article
- Cell cycle-dependent cues regulate temporal patterning of thebioRxiv : the preprint server for biology · 2025Article
- Reelin Controls the Directional Orientation, Apical Localization and Length of Primary Cilia in Principal Neurons in the Cerebral Cortex.bioRxiv : the preprint server for biology · 2025Article
- Epigenetic priming of neural progenitors by Notch enhances Sonic hedgehog signaling and establishes gliogenic competence.Genes & development · 2025Article
- NIR-Induced Photoswitching Hybrid DNA Nanoconstruct-Based Drug Delivery System for Spatiotemporal Control of Stem Cell Fate.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Hierarchical diversification of instinctual behavior neurons by lineage, birth order, and sex.bioRxiv : the preprint server for biology · 2025Article
- mCell stem cell · 2025Article
- Molecular profiling of invertebrate glia.Glia · 2025Review
- Posttranscriptional Control of Neural Progenitors Temporal Dynamics During Neocortical Development by Syncrip.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Design and Generation of TEMPO Reagents for Sequential Labeling and Manipulation of Vertebrate Cell Lineages.Methods in molecular biology (Clifton, N.J.) · 2025Article
- From genes to patterns: a framework for modeling the emergence of embryonic development from transcriptional regulation.Frontiers in cell and developmental biology · 2025Article
146 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The vast diversity of neurons and glia of the CNS is generated from a small, heterogeneous population of progenitors that undergo transcriptional changes during development to sequentially specify distinct cell fates. Guided by cell-intrinsic and -extrinsic cues, invertebrate and mammalian neural progenitors carefully regulate when and how many of each cell type is produced, enabling the formation of functional neural circuits. Emerging evidence indicates that neural progenitors also undergo changes in global chromatin architecture, thereby restricting when a particular cell type can be generated. Studies of temporal-identity specification and progenitor competence can provide insight into how we could use neural progenitors to more effectively generate specific cell types for brain repair.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.