ArticleFrontiers in public health2013
A Positive Association between T. gondii Seropositivity and Obesity.
Article in Frontiers in public health, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 49 citations in OpenAlex.
- Prevalence, incidence estimations, and risk factors of Toxoplasma gondii infection in Germany: a representative, cross-sectional, serological study.Scientific reports · 2016Trial
- Interplay of obesity and parasitic infection: current evidence of immunogenesis, tumorigenesis and leptin receptor involvement.Nutrition & metabolism · 2025Review
- Beyond Latency: ChronicBiomedicines · 2025Review
- The m6A demethylase FTO regulates TNF-α expression in human macrophages following Toxoplasma gondii infection.PLoS neglected tropical diseases · 2025Article
- Effects of diet and ovariectomy onBrain communications · 2025Article
- Toxoplasma gondii IgG serointensity and cognitive function in bipolar disorder.International journal of bipolar disorders · 2024Article
- Review
- Adverse pregnancy outcomes in Toxoplasma gondii seropositive Hispanic women.The journal of obstetrics and gynaecology research · 2023Article
- Infections and immunity: associations with obesity and related metabolic disorders.Journal of pathology and translational medicine · 2023Review
- Do Intestinal Unicellular Parasites Have a Role in the Inflammatory and Redox Status among the Severely Obese?Antioxidants (Basel, Switzerland) · 2022Article
- The Impact of LatentMicroorganisms · 2022Article
- The Immune Response in Adipocytes and Their Susceptibility to Infection: A Possible Relationship with Infectobesity.International journal of molecular sciences · 2022Review
- Orthorexia Nervosa in Adolescents and Young Adults: A Literature Review.Children (Basel, Switzerland) · 2022Review
- Cross-sectional association of Toxoplasma gondii exposure with BMI and diet in US adults.PLoS neglected tropical diseases · 2021Article
- Uncovering the complex genetics of human character.Molecular psychiatry · 2020Article
- Uncovering the complex genetics of human temperament.Molecular psychiatry · 2020Article
- The influence of exposure to Toxoplasma Gondii on host lipid metabolism.BMC infectious diseases · 2020Article
- Obesity impairs resistance to Leishmania major infection in C57BL/6 mice.PLoS neglected tropical diseases · 2020Article
- Is Toxoplasma gondii infection correlated with nonalcoholic fatty liver disease?- a population-based study.BMC infectious diseases · 2018Article
- No evidence for airborne transmission ofPteridines · 2018Article
Corrections and comments
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Authors and funding
15 authors at 9 institutions in 3 countries.
Funding
Abstract
Obesity is a global public health problem that is linked with morbidity, mortality, and functional limitations and has limited options for sustained interventions. Novel targets for prevention and intervention require further research into the pathogenesis of obesity. Consistently, elevated markers of inflammation have been reported in association with obesity, but their causes and consequences are not well understood. An emerging field of research has investigated the association of infections and environmental pathogens with obesity, potential causes of low grade inflammation that may mediate obesity risk. In this study, we estimate the possible association between Toxoplasma gondii (T. gondii) infection and obesity in a sample of 999 psychiatrically healthy adults. Individuals with psychiatric conditions, including personality disorders, were excluded because of the association between positive serology to T. gondii and various forms of serious mental illness that have a strong association with obesity. In our sample, individuals with positive T. gondii serology had twice the odds of being obese compared to seronegative individuals (p = 0.01). Further, individuals who were obese had significant higher T. gondii IgG titers compared to individuals who were non-obese. Latent T. gondii infection is very common worldwide, so potential public health interventions related to this parasite can have a high impact on associated health concerns.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.