ReviewFrontiers in cellular neuroscience2013
Recent molecular approaches to understanding astrocyte function in vivo.
Review in Frontiers in cellular neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed.
- Necroptosis in CNS diseases: Focus on astrocytes.Frontiers in aging neuroscience · 2022Review
- NDRG2 attenuates ischemia-induced astrocyte necroptosis via the repression of RIPK1.Molecular medicine reports · 2020Article
- Modeling vanishing white matter disease with patient-derived induced pluripotent stem cells reveals astrocytic dysfunction.CNS neuroscience & therapeutics · 2019Article
- Dopamine D2 receptor restricts astrocytic NLRP3 inflammasome activation via enhancing the interaction of β-arrestin2 and NLRP3.Cell death and differentiation · 2018Article
- Astrocytes integrate and drive action potential firing in inhibitory subnetworks.Nature communications · 2018Article
- 3,5,6,7,8,3',4'-Heptamethoxyflavone Ameliorates Depressive-Like Behavior and Hippocampal Neurochemical Changes in Chronic Unpredictable Mild Stressed Mice by Regulating the Brain-Derived Neurotrophic Factor: Requirement for ERK Activation.International journal of molecular sciences · 2017Article
- Hippocampal Astrocyte Cultures from Adult and Aged Rats Reproduce Changes in Glial Functionality Observed in the Aging Brain.Molecular neurobiology · 2017Article
- Phosphorylation of αB-crystallin supports reactive astrogliosis in demyelination.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Article
- Theoretical Approaches to Lentiviral Mediated Neurotrophin Delivery in Potential Treatments of Parkinson's Disease.The Yale journal of biology and medicine · 2016Review
- Targeted gene transfer to the brain via the delivery of brain-penetrating DNA nanoparticles with focused ultrasound.Journal of controlled release : official journal of the Controlled Release Society · 2016Article
- Maternal antibodies and developing blood-brain barrier.Immunologic research · 2015Review
- Astrocyte calcium signaling: from observations to functions and the challenges therein.Cold Spring Harbor perspectives in biology · 2015Review
- Elusive roles for reactive astrocytes in neurodegenerative diseases.Frontiers in cellular neuroscience · 2015Review
- In vivo tactile stimulation-evoked responses in Caenorhabditis elegans amphid sheath glia.PloS one · 2015Article
- Imaging intracellular Ca²⁺ signals in striatal astrocytes from adult mice using genetically-encoded calcium indicators.Journal of visualized experiments : JoVE · 2014Article
- Imaging and monitoring astrocytes in health and disease.Frontiers in cellular neuroscience · 2014Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Astrocytes are a predominant glial cell type in the nervous systems, and are becoming recognized as important mediators of normal brain function as well as neurodevelopmental, neurological, and neurodegenerative brain diseases. Although numerous potential mechanisms have been proposed to explain the role of astrocytes in the normal and diseased brain, research into the physiological relevance of these mechanisms in vivo is just beginning. In this review, we will summarize recent developments in innovative and powerful molecular approaches, including knockout mouse models, transgenic mouse models, and astrocyte-targeted gene transfer/expression, which have led to advances in understanding astrocyte biology in vivo that were heretofore inaccessible to experimentation. We will examine the recently improved understanding of the roles of astrocytes - with an emphasis on astrocyte signaling - in the context of both the healthy and diseased brain, discuss areas where the role of astrocytes remains debated, and suggest new research directions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.