ReviewClinical, cosmetic and investigational dermatology2013
Glycolic acid peel therapy - a current review.
Review in Clinical, cosmetic and investigational dermatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Comparative efficacy of topical interventions for facial photoaging: a network meta-analysis.Scientific reports · 2025Pooled it
- Topical, light-based, and complementary interventions for acne: an overview of systematic reviews.The Cochrane database of systematic reviews · 2024Pooled it
- Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne.The Cochrane database of systematic reviews · 2020Pooled it
- Chemical peels for acne vulgaris: a systematic review of randomised controlled trials.BMJ open · 2018Pooled it
- Enhancing Facial Rejuvenation Outcomes With a Novel Retinaldehyde-Based Cream: A Comparative Randomized Intra-Individual Study.Journal of cosmetic dermatology · 2025Trial
- Efficacy of combined 1927 nm thulium fiber laser and supramolecular salicylic acid in photoaging treatment.Lasers in medical science · 2025Trial
- Comparative study using fractional carbon dioxide laser versus glycolic acid peel in treatment of pseudo-acanthosis nigricans.Lasers in medical science · 2018Trial
- Simple and Scalable Electrochemical Reduction of Alkyl Oxalates Using Carbon-Based Electrodes.ChemSusChem · 2026Article
- Cosmeceuticals in acne vulgaris: from mechanism of action to clinical application.Skin health and disease · 2026Review
- From acidification to multi-targeted cellular modulation: dual impact of hydroxy acids on the skin microbiota and the epidermal barrier.Frontiers in cellular and infection microbiology · 2026Review
- Pd/C-Catalyzed Efficient and Selective Synthesis of Glycolic Acid from Ethylene Glycol.ChemSusChem · 2025Article
- Effective Skin Rejuvenation by a Novel Antioxidant Biostimulating Treatment.Journal of cosmetic dermatology · 2025Article
- Scar Management in Pediatric Patients.Medicina (Kaunas, Lithuania) · 2025Review
- Production of glycolic acid through whole-cell bioconversion from PET monomer ethylene glycol using engineered Corynebacterium glutamicum.Journal of industrial microbiology & biotechnology · 2024Article
- Degradable Polymeric Bio(nano)materials and Their Biomedical Applications: A Comprehensive Overview and Recent Updates.Polymers · 2024Review
- Case Series: Therapeutic Combination of VoluDerm Radiofrequency Microneedling and Glycolic Acid Peel in Scaled-Up Concentrations.Aesthetic surgery journal. Open forum · 2024Article
- Evaluating the Efficacy and Safety of Alpha-Hydroxy Acids in Dermatological Practice: A Comprehensive Clinical and Legal Review.Clinical, cosmetic and investigational dermatology · 2024Review
- A Comprehensive Bibliographic Review Concerning the Efficacy of Organic Acids for Chemical Peels Treating Acne Vulgaris.Molecules (Basel, Switzerland) · 2023Review
- Cosmetic Procedures in Patients with Skin of Color: Clinical Pearls and Pitfalls.The Journal of clinical and aesthetic dermatology · 2023Review
- Snail Slime Extracted by a Cruelty Free Method Preserves Viability and Controls Inflammation Occurrence: A Focus on Fibroblasts.Molecules (Basel, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chemical peels have been time-tested and are here to stay. Alpha-hydroxy peels are highly popular in the dermatologist's arsenal of procedures. Glycolic acid peel is the most common alpha-hydroxy acid peel, also known as fruit peel. It is simple, inexpensive, and has no downtime. This review talks about various studies of glycolic acid peels for various indications, such as acne, acne scars, melasma, postinflammatory hyperpigmentation, photoaging, and seborrhea. Combination therapies and treatment procedure are also discussed. Careful review of medical history, examination of the skin, and pre-peel priming of skin are important before every peel. Proper patient selection, peel timing, and neutralization on-time will ensure good results, with no side effects. Depth of the glycolic acid peel depends on the concentration of the acid used, the number of coats applied, and the time for which it is applied. Hence, it can be used as a very superficial peel, or even a medium depth peel. It has been found to be very safe with Fitzpatrick skin types I-IV. All in all, it is a peel that is here to stay.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.