ReviewGlycoconjugate journal2014
GM3 and diabetes.
Review in Glycoconjugate journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 47 citations in OpenAlex.
- Metabolic Analysis: Tracing Gangliosides and Precursors in Foods.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Ceramides are fuel gauges on the drive to cardiometabolic disease.Physiological reviews · 2024Review
- Spin-labeling Insights into How Chemical Fixation Impacts Glycan Organization on Cells.Applied magnetic resonance · 2024Article
- Possible involvement of sialidase and sialyltransferase activities in a stage-dependent recycling of sialic acid in some organs of type 1 and type 2 diabetic rats.Frontiers in endocrinology · 2024Article
- Stereochemistry of Sphingolipids in Ganglioside GM3 Enhances Recovery of Nervous Functionality.ACS medicinal chemistry letters · 2023Article
- Gangliosides as Biomarkers of Human Brain Diseases: Trends in Discovery and Characterization by High-Performance Mass Spectrometry.International journal of molecular sciences · 2022Review
- The Involvement of Lactosylceramide in Central Nervous System Inflammation Related to Neurodegenerative Disease.Frontiers in aging neuroscience · 2021Review
- Gangliosides in Podocyte Biology and Disease.International journal of molecular sciences · 2020Review
- Ganglioside deficiency in hypothalamic POMC neurons promotes body weight gain.International journal of obesity (2005) · 2020Article
- Dietary Control of Ganglioside Expression in Mammalian Tissues.International journal of molecular sciences · 2019Review
- Gangliosides: Treatment Avenues in Neurodegenerative Disease.Frontiers in neurology · 2019Review
- Induction of ganglioside synthesis in Drosophila brain accelerates assembly of amyloid β protein.Scientific reports · 2018Article
- Cerebral organoids derived from Sandhoff disease-induced pluripotent stem cells exhibit impaired neurodifferentiation.Journal of lipid research · 2018Article
- Insulin Receptor Isoforms in Physiology and Disease: An Updated View.Endocrine reviews · 2017Review
- Association between dairy intake, lipids and vascular structure and function in diabetes.World journal of diabetes · 2017Article
- Altered expression of ganglioside GM3 molecular species and a potential regulatory role during myoblast differentiation.The Journal of biological chemistry · 2017Article
- Ganglioside-Lipid and Ganglioside-Protein Interactions Revealed by Coarse-Grained and Atomistic Molecular Dynamics Simulations.The journal of physical chemistry. B · 2017Article
- Mice lacking sialyltransferase ST3Gal-II develop late-onset obesity and insulin resistance.Glycobiology · 2017Article
- Dissecting PUGNAc-mediated inhibition of the pro-survival action of insulin.Glycobiology · 2016Article
- Metabolic features of chronic fatigue syndrome.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We demonstrated the molecular pathogenesis of type 2 diabetes and insulin resistance focusing on the interaction between insulin receptor and GM3 ganglioside in adipocytes and propose a working hypothesis "metabolic disorders, such as type 2 diabetes, are membrane microdomain disorders caused by aberrant expression of gangliosides". It is expected that the development of novel diagnosis of metabolic syndrome by identifying the specific ganglioside species and a therapeutic strategy "membrane microdomain ortho-signaling therapy".
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.