ArticleJournal of trauma nursing : the official journal of the Society of Trauma Nurses
Increased mortality in adult patients with trauma transfused with blood components compared with whole blood.
Article in Journal of trauma nursing : the official journal of the Society of Trauma Nurses. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Inhospital coagulation management and fluid replacement therapy in patients with multiple and/or severe injuries - a systematic review and clinical practice guideline update.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Pooled it
- The use of whole blood in traumatic bleeding: a systematic review.Internal and emergency medicine · 2021Pooled it
- A Component Analysis of Endotheliopathy of Trauma.Research square · 2026Article
- Article
- Association between whole blood versus balanced component therapy and survival in isolated severe traumatic brain injury.Trauma surgery & acute care open · 2025Article
- Can heroic roadside care save lives?Trauma surgery & acute care open · 2025Review
- Anesthetic managements, morbidities and mortalities in retroperitoneal sarcoma patients experiencing perioperative massive blood transfusion.Frontiers in oncology · 2024Article
- Evolution of whole blood trauma resuscitation in childbearing age females: practice patterns and trends.Trauma surgery & acute care open · 2024Article
- Impact of Transfused Citrate on Pathophysiology in Massive Transfusion.Critical care explorations · 2023Review
- [The chapters "Stop the bleed-prehospital" and "Coagulation management and volume therapy (emergency departement)" in the new S3 guideline "Polytrauma/severe injury treatment"].Notfall & rettungsmedizin · 2023Review
- The Role of Whole Blood Transfusions in Civilian Trauma: A Review of Literature in Military and Civilian Trauma.Cureus · 2022Review
- Whole blood transfusion versus component therapy in trauma resuscitation: a systematic review and meta-analysis.Journal of the American College of Emergency Physicians open · 2020Article
- THE MANAGEMENT OF TRANSFUSION SERVICES, ANALYSIS AND ASSESSMENT.Materia socio-medica · 2016Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Hemorrhage is a preventable cause of death among patients with trauma, and management often includes transfusion, either whole blood or a combination of blood components (packed red blood cells, platelets, fresh frozen plasma). We used the 2009 National Trauma Data Bank data set to evaluate the relationship between transfusion type and mortality in adult patients with major trauma (n = 1745). Logistic regression analysis identified 3 independent predictors of mortality: Injury Severity Score, emergency medical system transfer time, and type of blood transfusion, whole blood or components. Transfusion of whole blood was associated with reduced mortality; thus, it may provide superior survival outcomes in this population.
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