Evidence map›Paper›PMID 24398454›Full record

ArticlePhysiological measurement2014

Effects of body mass index on gastric slow wave: a magnetogastrographic study.

S Somarajan, S Cassilly, C Obioha, W O Richards, L A Bradshaw

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Physiological measurement, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03176927 (Biomagnetic Characterization of Gastric Dysrhythmias III), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03176927 early_phase1completednot on this map

Biomagnetic Characterization of Gastric Dysrhythmias III

TypeinterventionalSponsorVanderbilt University Medical CenterRan2012 to 2021Enrolled22ConditionsDiabetics Without Symptoms of Gastroparesis, Diabetic Gastroparesis, Idiopathic Gastroparesis, Total or Partial GastrectomyArmsmagnetogastrogram
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

S SomarajanDepartment of Surgery, Vanderbilt University, Nashville, TN, USA. Department of Physics & Astronomy, Vanderbilt University, Nashville, TN, USA.
S Cassilly
C Obioha
W O Richards
L A Bradshaw
Vanderbilt University · USLipscomb University · USUniversity of South Alabama · US

Funding

BIOMAGNETIC CHARACTERIZATION OF GASTRIC DYSRHYTHMIASR01DK058697 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BRADSHAW, LEONARD A · 2001 to 2013
$3.1M
Biomagnetic Signals of Intestinal IschemiaR01DK058197 · NIDDK · VANDERBILT UNIVERSITY · PI RICHARDS, WILLIAM O · 2002 to 2009
$2.6M
NIDDK NIH HHS R01 DK058197NIDDK NIH HHS R01 DK058697NIDDK NIH HHS R01 DK58197NIDDK NIH HHS R01 DK58697
6 · The paper itself

Abstract

We measured gastric slow wave activity simultaneously with magnetogastrogram (MGG), mucosal electromyogram (EMG) and electrogastrogram (EGG) in human subjects with varying body mass index (BMI) before and after a meal. In order to investigate the effect of BMI on gastric slow wave parameters, each subject's BMI was calculated and divided into two groups: subjects with BMI ≤ 27 and BMI > 27. Signals were processed with Fourier spectral analysis and second-order blind identification (SOBI) techniques. Our results showed that increased BMI does not affect signal characteristics such as frequency and amplitude of EMG and MGG. Comparison of the postprandial EGG power, on the other hand, showed a statistically significant reduction in subjects with BMI > 27 compared with BMI ≤ 27. In addition to the frequency and amplitude, the use of SOBI-computed propagation maps from MGG data allowed us to visualize the propagating slow wave and compute the propagation velocity in both BMI groups. No significant change in velocity with increasing BMI or meal was observed in our study. In conclusion, multichannel MGG provides an assessment of frequency, amplitude and propagation velocity of the slow wave in subjects with differing BMI categories and was observed to be independent of BMI.

Indexed as

Body Mass IndexGastrointestinal MotilityMagnetic FieldsAdolescentAdultElectrodesElectrophysiologyFemaleGastric MucosaHumansMaleMiddle AgedYoung Adult

Identifiers

PMID24398454
PMCPMC4012612
OpenAlexW2163114777

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.