ArticleJournal of molecular evolution1987
Evolution of keratin genes: different protein domains evolve by different pathways.
Article in Journal of molecular evolution, 1987. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 66 citations in OpenAlex.
- Unique amino acid signatures that are evolutionarily conserved distinguish simple-type, epidermal and hair keratins.Journal of cell science · 2011Article
- Isolation and chromosomal localization of a cornea-specific human keratin 12 gene and detection of four mutations in Meesmann corneal epithelial dystrophy.American journal of human genetics · 1997Article
- Isolation and characterization of sulfur globule proteins from Chromatium vinosum and Thiocapsa roseopersicina.Archives of microbiology · 1995Article
- Isolation and characterization of a cartilage-specific membrane antigen (CH65): comparison with cytokeratins and heat-shock proteins.Immunology · 1994Article
- Epidermal growth factor and transforming growth factor alpha specifically induce the activation- and hyperproliferation-associated keratins 6 and 16.Proceedings of the National Academy of Sciences of the United States of America · 1993Article
- Mycobacterial 65,000 MW heat-shock protein shares a carboxy-terminal epitope with human epidermal cytokeratin 1/2.Immunology · 1992Article
- Concerted gene duplications in the two keratin gene families.Journal of molecular evolution · 1988Article
- Domain organization and intron positions in Caenorhabditis elegans collagen genes: the 54-bp module hypothesis revisited.Journal of molecular evolutionArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Intermediate filaments are composed of a family of proteins that evolved from a common ancestor. The proteins consist of three domains: a central, alpha-helical domain similar in all intermediate filaments, bracketed by two domains that are variable in length and structure. Within the intermediate-filament family, several subfamilies have been recognized by immunologic and nucleic acid hybridization techniques. In this paper we present the sequence of the genomic DNA coding for a 65-kilodalton human keratin and compare it with the sequences of other intermediate-filament proteins. While the central, alpha-helical domains of these proteins show homologies that indicate a common ancestor, the sequences of the variable terminal domains indicate that the variable domains evolved through a series of tandem duplications and possibly by gene-conversion mechanisms.
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