ReviewAnatomy research international2013
The maze of the cerebrospinal fluid discovery.
Review in Anatomy research international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Leonardo di ser piero da Vinci-a bridge between ancient and post-Galenic anatomy based on studies of the ventricular system of the brain.Frontiers in neuroanatomy · 2026Review
- PTEN mutations impair CSF dynamics and cortical networks by dysregulating periventricular neural progenitors.Nature neuroscience · 2025Article
- Cerebrospinal Fluid-Basic Concepts Review.Biomedicines · 2023Review
- Measurements of cerebrospinal fluid production: a review of the limitations and advantages of current methodologies.Fluids and barriers of the CNS · 2022Review
- A new perspective on cerebrospinal fluid dynamics after subarachnoid hemorrhage: From normal physiology to pathophysiological changes.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022Review
- Fluid transport in the brain.Physiological reviews · 2022Review
- The historic evolution of intracranial pressure and cerebrospinal fluid pulse pressure concepts: Two centuries of challenges.Surgical neurology international · 2021Review
- Changing the Currently Held Concept of Cerebrospinal Fluid Dynamics Based on Shared Findings of Cerebrospinal Fluid Motion in the Cranial Cavity Using Various Types of Magnetic Resonance Imaging Techniques.Neurologia medico-chirurgica · 2019Review
- Massa versus Haller: Priority of the Cerebrospinal Fluid Discovery.Neurologia medico-chirurgica · 2018Article
- Respiration: A New Mechanism for CSF Circulation?The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Cerebrospinal fluid and lumbar puncture: the story of a necessary procedure in the history of medicine.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2015Article
- Imhotep and the discovery of cerebrospinal fluid.Anatomy research international · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The author analyzes a historical, long, and tortuous way to discover the cerebrospinal fluid. At least 35 physicians and anatomists described in the text have laid the fundamentals of recognition of this biological fluid's presence. On the basis of crucial anatomical, experimental, and clinical works there are four greatest physicians who should be considered as equal cerebrospinal fluid's discoverers: Egyptian Imhotep, Venetian Nicolo Massa, Italian Domenico Felice Cotugno, and French François Magendie.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.