Evidence map›Paper›PMID 24396497›Full record

ReviewJournal of Cancer2014

Future directions for monitoring treatment response in colorectal cancer.

Avery S Walker, Nathan P Zwintscher, Eric K Johnson, Justin A Maykel, Alexander Stojadinovic, Aviram Nissan, Itzhak Avital, Björn Ldm Brücher, Scott R Steele

Abstract readReview
In one paragraph

Review in Journal of Cancer, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. How Should Imaging Direct/Orient Management of Rectal Cancer?Clinics in colon and rectal surgery · 2017
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Early detection of colorectal cancer: from conventional methods to novel biomarkers.Journal of cancer research and clinical oncology · 2016
    Review
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Avery S Walker1. Department of Surgery, Madigan Army Medical Center, 9040 Fitzsimmons Dr., Fort Lewis, WA, USA.
Nathan P Zwintscher1. Department of Surgery, Madigan Army Medical Center, 9040 Fitzsimmons Dr., Fort Lewis, WA, USA.
Eric K Johnson1. Department of Surgery, Madigan Army Medical Center, 9040 Fitzsimmons Dr., Fort Lewis, WA, USA.
Justin A Maykel2. University of Massachusetts Memorial Medical Center, Worcester, MA, USA.
Alexander Stojadinovic3. Department of Surgery, Division of Surgical Oncology, Walter Reed National Military Medical Center, Bethesda, MD, USA.
Aviram Nissan4. Department of Surgery, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Itzhak Avital5. Bon Secours Cancer Institute, Richmond, VA, USA.
Björn Ldm Brücher5. Bon Secours Cancer Institute, Richmond, VA, USA.
Scott R Steele1. Department of Surgery, Madigan Army Medical Center, 9040 Fitzsimmons Dr., Fort Lewis, WA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment of advanced colon and rectal cancer has significantly evolved with the introduction of neoadjuvant chemoradiation therapy so much that, along with more effective chemotherapy regimens, surgery has been considered unnecessary among some institutions for select patients. The tumor response to these treatments has also improved and ultimately has been shown to have a direct effect on prognosis. Yet, the best way to monitor that response, whether clinically, radiologically, or with laboratory findings, remains controversial. The authors' aim is to briefly review the options available and, more importantly, examine emerging and future options to assist in monitoring treatment response in cases of locally advanced rectal cancer and metastatic colon cancer.

Indexed as

biomarkersColorectal cancerimaging modalitiesresponsesurgical timingwatch and wait

Identifiers

PMID24396497
PMCPMC3881220

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.