Evidence map›Paper›PMID 24396219›Full record

ArticleJournal of physical therapy science2013

On the functional capacity and quality of life of patients with acromegaly: are they candidates for rehabilitation programs?

Débora Pedroza Guedes da Silva, Fernando Silva Guimarães, Cristina Márcia Dias, Simone de Araujo Guimarães, Leandro Kasuki, Mônica Roberto Gadelha, Gustavo Bittencourt Camilo, Agnaldo José Lopes

Abstract read
In one paragraph

Article in Journal of physical therapy science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Fatigue in acromegaly patients: a scoping review.Frontiers in endocrinology · 2025
    Article
  3. Observational
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Débora Pedroza Guedes da SilvaRehabilitation Sciences Master's Program, Augusto Motta University Center, Brazil.
Fernando Silva GuimarãesRehabilitation Sciences Master's Program, Augusto Motta University Center, Brazil.
Cristina Márcia DiasRehabilitation Sciences Master's Program, Augusto Motta University Center, Brazil.
Simone de Araujo GuimarãesRehabilitation Sciences Master's Program, Augusto Motta University Center, Brazil.
Leandro KasukiDepartment of Endocrinology, Federal University of Rio de Janeiro, Brazil.
Mônica Roberto GadelhaDepartment of Endocrinology, Federal University of Rio de Janeiro, Brazil.
Gustavo Bittencourt CamiloDepartment of Radiology, State University of Rio de Janeiro, Brazil.
Agnaldo José LopesRehabilitation Sciences Master's Program, Augusto Motta University Center, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

[Purpose] This study compared patients having active acromegaly with those having controlled acromegaly in terms of peripheral muscle strength, body composition, and functional capacity. We also examined the associations between these measures. [Methods] A total of 14 patients with active acromegaly, 12 patients with controlled acromegaly, and 12 healthy controls were subjected to isometric dynamometry, surface electromyography, electrical bioimpedance, and a six-minute walk test. [Results] The active acromegaly group exhibited significantly more fat-free mass than the control group. With respect to the peripheral muscle performance, the controlled acromegaly group presented a significantly lower electromyographic median frequency than the control group. The quadriceps maximum strength was significantly lower in the controlled acromegaly group than in the control group. The fat-free mass was significantly correlated with the quadriceps maximum strength. The global scores of the Acromegaly Quality of Life Questionnaire were significantly correlated with the six-minute walk distance. [Conclusion] Patients with acromegaly have more fat-free mass, less peripheral muscle strength, and greater fatigability than healthy control subjects. These findings depend on the degree of hormonal control. In acromegalic patients, peripheral muscle strength is related to body composition, and functional capacity is correlated with quality of life.

Indexed as

AcromegalyExercise toleranceMuscle strength

Identifiers

PMID24396219
PMCPMC3881486

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.