Evidence map›Paper›PMID 24396139›Full record

ReviewClinical microbiology reviews2014

Hepatitis E virus infection.

Nassim Kamar, Harry R Dalton, Florence Abravanel, Jacques Izopet

Open access · bronzeAbstract readReview
In one paragraph

Review in Clinical microbiology reviews, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 274 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
274citing papers in PubMed, 8 pooled it
31.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

274 citing papers in PubMed, 8 syntheses or guidelines pooled it, 652 citations in OpenAlex.

  1. Pooled it
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  4. Pooled it
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  6. Pooled it
  7. Guideline
  8. Pooled it
  9. Trial
  10. Review
  11. Review
  12. Article
  13. Article
  14. Traveling with chronic viral hepatitis.Tropical diseases, travel medicine and vaccines · 2026
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Hepatitis E virus infection in a single center in Japan.Clinical and experimental hepatology · 2026
    Article
  20. Article

214 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Nassim KamarDepartment of Nephrology and Organ Transplantation, CHU Rangueil, Toulouse, France.
Harry R Dalton
Florence Abravanel
Jacques Izopet
Université Toulouse III - Paul Sabatier · FRInserm · FRUniversity of Exeter · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis E virus (HEV) infection is a worldwide disease. An improved understanding of the natural history of HEV infection has been achieved within the last decade. Several reservoirs and transmission modes have been identified. Hepatitis E is an underdiagnosed disease, in part due to the use of serological assays with low sensitivity. However, diagnostic tools, including nucleic acid-based tests, have been improved. The epidemiology and clinical features of hepatitis E differ between developing and developed countries. HEV infection is usually an acute self-limiting disease, but in developed countries it causes chronic infection with rapidly progressive cirrhosis in organ transplant recipients, patients with hematological malignancy requiring chemotherapy, and individuals with HIV. HEV also causes extrahepatic manifestations, including a number of neurological syndromes and renal injury. Acute infection usually requires no treatment, but chronic infection should be treated by reducing immunosuppression in transplant patients and/or the use of antiviral therapy. In this comprehensive review, we summarize the current knowledge about the virus itself, as well as the epidemiology, diagnostics, natural history, and management of HEV infection in developing and developed countries.

Indexed as

Hepatitis EChronic DiseaseDeveloped CountriesDeveloping CountriesDisease ReservoirsHepatitis E virusHumans

Identifiers

PMID24396139
PMCPMC3910910
OpenAlexW2127999679

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.