ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2014
Rates and determinants of seasonal influenza vaccination in pregnancy and association with neonatal outcomes.
Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 8 of them syntheses that pooled it.
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Who cites it
65 citing papers in PubMed, 8 syntheses or guidelines pooled it, 112 citations in OpenAlex.
- Pooled it
- How effective are digital interventions in increasing flu vaccination among pregnant women? A systematic review and meta-analysis.Journal of public health (Oxford, England) · 2022Pooled it
- One "misunderstood" health issue: demonstrating and communicating the safety of influenza a vaccination in pregnancy: a systematic review and meta-analysis.BMC public health · 2021Pooled it
- The safety of inactivated influenza vaccines in pregnancy for birth outcomes: a systematic review.Human vaccines & immunotherapeutics · 2019Pooled it
- Effects of maternal influenza vaccination on adverse birth outcomes: A systematic review and Bayesian meta-analysis.PloS one · 2019Pooled it
- Guideline
- Neonatal death: Case definition & guidelines for data collection, analysis, and presentation of immunization safety data.Vaccine · 2016Guideline
- Use of existing systematic reviews for evidence assessments in infectious disease prevention: a comparative case study.Systematic reviews · 2016Pooled it
- Efficacy, duration of protection, birth outcomes, and infant growth associated with influenza vaccination in pregnancy: a pooled analysis of three randomised controlled trials.The Lancet. Respiratory medicine · 2020Trial
- Trivalent influenza vaccination randomized control trial of pregnant women and adverse fetal outcomes.Vaccine · 2019Trial
- Contribution of Serologic Assays in the Evaluation of Influenza Virus Infection Rates and Vaccine Efficacy in Pregnant Women: Report From Randomized Controlled Trials.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017Trial
- Decoding neurodevelopment risks of exposures to intoxication, infection, and trauma during pregnancy.Pregnancy (Hoboken, N.J.) · 2026Review
- Maternal influenza vaccination intention and associated factors among pregnant women in Guizhou Province, China.Human vaccines & immunotherapeutics · 2025Article
- Evaluating the Protective Effects of Influenza Vaccination in Pregnant Women and Their Infants: An Umbrella Review.Iranian journal of public health · 2025Review
- Transcriptome analysis in human breast milk and blood in a randomized trial after inactivated or attenuated influenza immunization.NPJ vaccines · 2025Article
- Defining and reporting adverse events of special interest in comparative maternal vaccine studies: a systematic review.Vaccine: X · 2024Review
- Characteristics and determinants of seasonal influenza vaccination in Manitoba, Canada: A population-wide record-linkage study.Vaccine: X · 2024Article
- Article
- Maternal Vaccination to Prevent Adverse Pregnancy Outcomes: An Underutilized Molecular Immunological Intervention?Journal of molecular biology · 2023Review
- Article
5 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is growing evidence that seasonal influenza vaccination in pregnancy has benefits for mother and baby. We determined influenza vaccination rates among pregnant women during the 2 nonpandemic influenza seasons following the 2009 H1N1 pandemic, explored maternal factors as predictors of influenza vaccination status and evaluated the association between maternal influenza vaccination and neonatal outcomes.
methodsWe used a population-based perinatal database in the province of Nova Scotia, Canada, to examine maternal vaccination rates, determinants of vaccination status and neonatal outcomes. Our cohort included women who gave birth between Nov. 1, 2010, and Mar. 31, 2012. We compared neonatal outcomes between vaccinated and unvaccinated women using logistic regression analysis.
resultsOverall, 1958 (16.0%) of 12,223 women in our cohort received the influenza vaccine during their pregnancy. Marital status, parity, location of residence (rural v. urban), smoking during pregnancy and maternal influenza risk status were determinants of maternal vaccine receipt. The odds of preterm birth was lower among infants of vaccinated women than among those of nonvaccinated women (adjusted odds ratio [OR] 0.75, 95% confidence interval [CI] 0.60-0.94). The rate of low-birth-weight infants was also lower among vaccinated women (adjusted OR 0.73, 95% CI 0.56-0.95).
interpretationDespite current guidelines advising all pregnant women to receive the seasonal influenza vaccine, influenza vaccination rates among pregnant women in our cohort were low in the aftermath of the 2009 H1N1 pandemic. This study and others have shown an association between maternal influenza vaccination and improved neonatal outcomes, which supports stronger initiatives to promote vaccination during pregnancy.
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