Evidence map›Paper›PMID 24395586›Full record

ArticleJournal of biomedical optics2014

Retrospective respiration-gated whole-body photoacoustic computed tomography of mice.

Jun Xia, Wanyi Chen, Konstantin Maslov, Mark A Anastasio, Lihong V Wang

Open access · bronzeAbstract read
In one paragraph

Article in Journal of biomedical optics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Regional motion correction forBiomedical optics express · 2021
    Article
  10. [Progress of motion artifact correction in photoacoustic microscopy and photoacoustic tomography].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2021
    Article
  11. Deep learning in photoacoustic imaging: a review.Journal of biomedical optics · 2021
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Tutorial on photoacoustic tomography.Journal of biomedical optics · 2016
    Review
  18. Review
  19. Photoacoustic tomography: principles and advances.Electromagnetic waves (Cambridge, Mass.)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jun Xia
Wanyi Chen
Konstantin Maslov
Mark A Anastasio
Lihong V Wang
Washington University in St. Louis · US

Funding

PHOTON TUNNELING: SHEDDING NEW LIGHT ON BIOMEDICINEDP1EB016986 · NIBIB · WASHINGTON UNIVERSITY · PI WANG, LIHONG · 2012 to 2016
$3.8M
PHOTOACOUSTIC MICROSCOPY OF NEOVASCULARIZATION IN RENAL CANCER GROWTH AND THERAPYR01CA159959 · NCI · WASHINGTON UNIVERSITY · PI ARBEIT, JEFFREY MICHAEL · 2011 to 2015
$2.9M
Monitoring of Breast Neoadjuvant Therapy by Thermo- and Photo- Acoustic TomographR01CA134539 · NCI · WASHINGTON UNIVERSITY · PI MONSEES, BARBARA, WANG, LIHONG · 2009 to 2013
$2.9M
WHOLE-BODY SMALL-ANIMAL PHOTOACOUSTIC-ULTRASONIC COMPUTED TOMOGRAPHYR01EB016963 · NIBIB · WASHINGTON UNIVERSITY · PI ANASTASIO, MARK A · 2013 to 2016
$2.4M
Development of Thermoacoustic Tomography Brain ImagingR01EB010049 · NIBIB · WASHINGTON UNIVERSITY · PI ANASTASIO, MARK A · 2010 to 2013
$1.6M
NCCDPHP CDC HHS DP1 EB016986NCI NIH HHS R01 CA134539NCI NIH HHS R01 CA159959NIBIB NIH HHS DP1 EB016986NIBIB NIH HHS R01 EB010049NIBIB NIH HHS R01 EB016963
6 · The paper itself

Abstract

Photoacoustic tomography (PAT) is an emerging technique that has a great potential for preclinical whole-body imaging. To date, most whole-body PAT systems require multiple laser shots to generate one cross-sectional image, yielding a frame rate of <1  Hz. Because a mouse breathes at up to 3 Hz, without proper gating mechanisms, acquired images are susceptible to motion artifacts. Here, we introduce, for the first time to our knowledge, retrospective respiratory gating for whole-body photoacoustic computed tomography. This new method involves simultaneous capturing of the animal's respiratory waveform during photoacoustic data acquisition. The recorded photoacoustic signals are sorted and clustered according to the respiratory phase, and an image of the animal at each respiratory phase is reconstructed subsequently from the corresponding cluster. The new method was tested in a ring-shaped confocal photoacoustic computed tomography system with a hardware-limited frame rate of 0.625 Hz. After respiratory gating, we observed sharper vascular and anatomical images at different positions of the animal body. The entire breathing cycle can also be visualized at 20  frames/cycle.

Indexed as

Photoacoustic TechniquesRespirationAcousticsAlgorithmsAnimalsBiosensing TechniquesEquipment DesignImage Processing, Computer-AssistedLiverMiceMotionPhotochemistryPressureTomography, X-Ray ComputedWhole Body Imaging

Identifiers

PMID24395586
PMCPMC3881607
OpenAlexW2061591189

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.