ArticleChemical communications (Cambridge, England)2014
Enzyme-triggered gelation: targeting proteases with internal cleavage sites.
Article in Chemical communications (Cambridge, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Solid-Phase Synthesis of 2-Benzothiazolyl and 2-(Aminophenyl)benzothiazolyl Amino Acids and Peptides.Molecules (Basel, Switzerland) · 2023Article
- Formation Mechanism and Biomedical Applications of Protease-Manipulated Peptide Assemblies.Frontiers in bioengineering and biotechnology · 2021Review
- Matrix metalloprotein-triggered, cell penetrating peptide-modified star-shaped nanoparticles for tumor targeting and cancer therapy.Journal of nanobiotechnology · 2020Article
- Dual functional matrix metalloproteinase-responsive curcumin-loaded nanoparticles for tumor-targeted treatment.Drug delivery · 2019Article
- Stimuli-Responsive Supramolecular Hydrogels and Their Applications in Regenerative Medicine.Macromolecular bioscience · 2019Review
- Enzyme-Instructed Self-Assembly of Peptides Containing Phosphoserine to Form Supramolecular Hydrogels as Potential Soft Biomaterials.Frontiers of chemical science and engineering · 2017Article
- Gd(III)-induced Supramolecular Hydrogelation with Enhanced Magnetic Resonance Performance for Enzyme Detection.Scientific reports · 2017Article
- Engineering responsive supramolecular biomaterials: Toward smart therapeutics.Bioengineering & translational medicine · 2016Review
- Supramolecular biomaterials.Nature materials · 2016Review
- My maize and blue brick road to physical organic chemistry in materials.Beilstein journal of organic chemistry · 2016Review
- Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials.Chemical reviews · 2015Review
- D-amino acids modulate the cellular response of enzymatic-instructed supramolecular nanofibers of small peptides.Biomacromolecules · 2014Article
- Supramolecular assemblies of a conjugate of nucleobase, amino acids, and saccharide act as agonists for proliferation of embryonic stem cells and development of zygotes.Bioconjugate chemistry · 2014Article
- Enzyme-instructed self-assembly of hydrogelators consisting of nucleobases, amino acids, and saccharide.RSC advances · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
A generalizable method for detecting protease activity via gelation is described. A recognition sequence is used to target the protease of interest while a second protease is used to remove the residual residues from the gelator scaffold. Using this approach, selective assays for both MMP-9 and PSA are demonstrated.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.