ArticleNature reviews. Endocrinology2014
Diabetes: Targeting endoplasmic reticulum to combat juvenile diabetes.
Article in Nature reviews. Endocrinology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed.
- WFS1-related isolated diabetes induced by a WFS1 missense mutation: focus on the isolated diabetes phenotype.Orphanet journal of rare diseases · 2026Article
- Pharmacological and non-pharmacological modulation of endoplasmic reticulum stress in pediatric diabetes.Frontiers in endocrinology · 2025Review
- Multidimensional analysis and therapeutic development using patient iPSC-derived disease models of Wolfram syndrome.JCI insight · 2022Article
- Adrenomedullin and its receptors are expressed in mouse pancreatic β-cells and suppresses insulin synthesis and secretion.PloS one · 2022Article
- Monogenic and syndromic diabetes due to endoplasmic reticulum stress.Journal of diabetes and its complications · 2021Article
- A soluble endoplasmic reticulum factor as regenerative therapy for Wolfram syndrome.Laboratory investigation; a journal of technical methods and pathology · 2020Article
- Pancreatic stone protein/regenerating protein is a potential biomarker for endoplasmic reticulum stress in beta cells.Scientific reports · 2019Article
- Wolfram Syndrome: Diagnosis, Management, and Treatment.Current diabetes reports · 2016Review
- IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions.Science signaling · 2015Article
- A calcium-dependent protease as a potential therapeutic target for Wolfram syndrome.Proceedings of the National Academy of Sciences of the United States of America · 2014 · on this mapArticle
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Authors and funding
1 author.
Funding
Abstract
Limited options for clinical management of patients with juvenile-onset diabetes mellitus call for a novel therapeutic paradigm. Two innovative studies support endoplasmic reticulum as an emerging target for combating both autoimmune and heritable forms of this disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.