Evidence map›Paper›PMID 24392801›Full record

ArticleChild development

Word reading fluency: role of genome-wide single-nucleotide polymorphisms in developmental stability and correlations with print exposure.

Nicole Harlaar, Maciej Trzaskowski, Philip S Dale, Robert Plomin

Abstract readTwin Study
In one paragraph

Article in Child development. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Genome-Wide Polygenic Scores Predict Reading Performance Throughout the School Years.Scientific studies of reading : the official journal of the Society for the Scientific Study of Reading · 2017
    Article
  6. Continuity and Stability in Development.Child development perspectives · 2017
    Article
  7. Article
  8. Stability of core language skill across the first decade of life in children at biological and social risk.Journal of child psychology and psychiatry, and allied disciplines · 2016
    Article
  9. Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nicole HarlaarUniversity of Colorado Boulder.
Maciej TrzaskowskiKing's College London.
Philip S DaleUniversity of New Mexico.
Robert PlominKing's College London.

Funding

Genetics, School environments and cognitive developmentR01HD044454 · NICHD · KING'S COLLEGE LONDON · PI PLOMIN, ROBERT · 2005 to 2014
$3.4M
Genetics of Mathematical Cognition and DisabilitiesR01HD059215 · NICHD · OHIO STATE UNIVERSITY · PI PETRILL, STEPHEN A. · 2009 to 2012
$2.4M
European Research Council 295366Medical Research Council G0500079Medical Research Council G0500079(73692)Medical Research Council G0901245Medical Research Council G19/2Medical Research Council G19/2(78332)NICHD NIH HHS HD044454NICHD NIH HHS HD059215NICHD NIH HHS R01 HD044454NICHD NIH HHS R01 HD059215Wellcome TrustWellcome Trust 085475/B/08/ZWellcome Trust 085475/Z/08/Z
6 · The paper itself

Abstract

The genetic effects on individual differences in reading development were examined using genome-wide complex trait analysis (GCTA) in a twin sample. In unrelated individuals (one twin per pair, n = 2,942), the GCTA-based heritability of reading fluency was ~20%-29% at ages 7 and 12. GCTA bivariate results showed that the phenotypic stability of reading fluency from 7 to 12 years (r = 0.69) is largely driven by genetic stability (genetic r = 0.69). Genetic effects on print exposure at age 12 were moderate (~26%) and correlated with those influencing reading fluency at 12 (genetic r = 0.89), indicative of a gene-environment correlation. These findings were largely consistent with quantitative genetic twin analyses that used both twins in each pair (n = 1,066-1,409).

Indexed as

Gene-Environment InteractionGenome-Wide Association StudyIndividualityReadingChildChild DevelopmentFemaleHumansMalePolymorphism, Single Nucleotide

Identifiers

PMID24392801
PMCPMC4064251

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.