ArticleJournal of natural products2014
4-Quinolone alkaloids from Melochia odorata.
Article in Journal of natural products, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Curative antimalarial efficacy and hepato-renal protective effects ofPharmaceutical science advances · 2025Article
- Alkaloids fromInternational journal of molecular sciences · 2024Review
- Quinolone: a versatile therapeutic compound class.Molecular diversity · 2023Review
- Hypervalent Iodine(III)-Promoted C3-H Regioselective Halogenation of 4-Quinolones under Mild Conditions.ACS omega · 2021Article
- Progress of Plant Medicine Derived Extracts and Alkaloids on Modulating Viral Infections and Inflammation.Drug design, development and therapy · 2021Review
- Paliasanines A-E, 3,4-Methylenedioxyquinoline Alkaloids Fused with a Phenyl-14-oxabicyclo[3.2.1]octane Unit fromJournal of natural products · 2020Article
- Cooperative Catalysis for the Highly Diastereo- and Enantioselective [4+3]-Cycloannulation of ortho-Quinone Methides and Carbonyl Ylides.Angewandte Chemie (International ed. in English) · 2020Article
- Synthesis and X-ray study of dispiro 8-nitroquinolone analogues and their cytotoxic properties against human cervical cancer HeLa cells.MedChemComm · 2019Article
- Cyclopropanation-ring expansion of 3-chloroindoles with α-halodiazoacetates: novel synthesis of 4-quinolone-3-carboxylic acid and norfloxacin.Beilstein journal of organic chemistry · 2019Article
- Biologically active quinoline and quinazoline alkaloids part II.Medicinal research reviews · 2018Review
- Catalytic Enantioselective Intermolecular [5 + 2] Dipolar Cycloadditions of a 3-Hydroxy-4-pyrone-Derived Oxidopyrylium Ylide.Organic letters · 2017Article
- Synthesis of first ever 4-quinolone-3-carboxylic acid-appended spirooxindole-pyrrolidine derivatives and their biological applications.Molecular diversity · 2017Article
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Authors and funding
8 authors.
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Abstract
The methanol extract of Melochia odorata yielded three 4-quinolone alkaloids including waltherione A (1) and two new alkaloids, waltherione C (2) and waltherione D (3). Waltheriones A and C showed significant activities in an in vitro anti-HIV cytoprotection assay at concentrations of 56.2 and 0.84 μM and inhibition of HIV P24 formation of more than 50% at 1.7 and 0.95 μM, respectively. The structures of the alkaloids were established by spectroscopic data interpretation.
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