ReviewFrontiers in cellular and infection microbiology2013
Drosophila at the intersection of infection, inflammation, and cancer.
Review in Frontiers in cellular and infection microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Tumor-Associated Macrophages Promote Brain Metastasis.bioRxiv : the preprint server for biology · 2026Article
- Using Drosophila to uncover the role of organismal physiology and the tumor microenvironment in cancer.Trends in cancer · 2024Review
- Exploration of Antimicrobial Peptides in the Treatment of Gentamicin-ResistantInfection and drug resistance · 2024Article
- Professional phagocytes are recruited for the clearance of obsolete nonprofessional phagocytes in theFrontiers in immunology · 2024Article
- Transcriptome of the pygmy grasshopperPeerJ · 2023Article
- Review
- Tumor Allotransplantation in Drosophila melanogaster with a Programmable Auto-Nanoliter Injector.Journal of visualized experiments : JoVE · 2021Article
- Proteome of the Triatomine Digestive Tract: From Catalytic to Immune Pathways; Focusing on Annexin Expression.Frontiers in molecular biosciences · 2020Article
- Animal Models to Study Cancer and Its Microenvironment.Advances in experimental medicine and biology · 2020Review
- Pro-apoptotic and pro-proliferation functions of the JNK pathway of Drosophila: roles in cell competition, tumorigenesis and regeneration.Open biology · 2019Review
- Review
- Overexpression of antimicrobial peptides contributes to aging through cytotoxic effects in Drosophila tissues.Archives of insect biochemistry and physiology · 2018Article
- The gestational power of mast cells in the injured tissue.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2018Review
- Learning on the Fly: The Interplay between Caspases and Cancer.BioMed research international · 2018Review
- Modelling Cooperative Tumorigenesis inBioMed research international · 2018Review
- Grow With the Challenge - Microbial Effects on Epithelial Proliferation, Carcinogenesis, and Cancer Therapy.Frontiers in microbiology · 2018Review
- The Immune Phenotype of ThreeG3 (Bethesda, Md.) · 2017Article
- The orange spotted cockroach (Proceedings of the West Virginia Academy of Science · 2017Article
- The danger model approach to the pathogenesis of the rheumatic diseases.Journal of immunology research · 2015Review
- Sterile inflammation in Drosophila.Mediators of inflammation · 2015Review
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Recent studies show that both cellular and humoral aspects of innate immunity play important roles during tumor progression. These interactions have traditionally been explored in vertebrate model systems. In recent years, Drosophila has emerged as a genetically tractable model system for studying key aspects of tumorigenesis including proliferation, invasion, and metastasis. The absence of adaptive immunity in Drosophila provides a unique opportunity to study the interactions between innate immune system and cancer in different genetic contexts. In this review, I discuss recent advances made by using Drosophila models of cancer to study the role of innate immune pathways Toll/Imd, JNK, and JAK-STAT, microbial infection and inflammation during tumor progression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.