ArticleInternational journal of ophthalmology2013
Pathological, immunohistochemical and microbiologicalal analysis of lacrimal sac biopsies in patients with chronic dacrocystitis.
Article in International journal of ophthalmology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Bacterial profile of ocular infections: a systematic review.BMC ophthalmology · 2017Pooled it
- Cellular and molecular mechanisms of nasolacrimal duct obstruction: New insights into CD4Journal of advanced research · 2026Article
- Evaluation of inflammation-related histopathological changes in the lacrimal sac, nasal bone, and nasal mucosa in cases of primary acquired nasolacrimal duct obstruction.International ophthalmology · 2026Article
- The Impact of Systemic Inflammation on Recurrence in Patients with Congenital Nasolacrimal Duct Obstruction.Journal of clinical medicine · 2024Article
- Dacryocystitis and canaliculitis secondary to residual of epidural catheter remaining in lacrimal duct for 25 years: a case report and literature review.International journal of ophthalmology · 2024Article
- Microbial distributions in the conjunctiva and lacrimal sacs of patients with chronic dacryocystitis in a tertiary hospital.International ophthalmology · 2023Article
- The influence of microorganisms on early relapses after external dacryocystorhinostomy.International ophthalmology · 2023Article
- The role of inflammatory biomarkers in predicting primary acquired nasolacrimal duct obstruction and postoperative recurrence.Nagoya journal of medical science · 2023Article
- The protective effect of URP20 on ocular Staphylococcus aureus and Escherichia coli infection in rats.BMC ophthalmology · 2022Article
- Differently Expressed Circular RNAs in Lacrimal Sacs From Patients With Chronic Dacryocystitis.Frontiers in genetics · 2022Article
- The predictive value of nasolacrimal sac biopsy in endoscopic dacryocystorhinostomy.Annals of medicine and surgery (2012) · 2021Article
- The microbiologic spectrum of dacryocystitis.BMC ophthalmology · 2021Article
- Bacterial agents and changes in drug susceptibilities in cases of chronic dacryocystitis, Southern China.International ophthalmology · 2021Article
- Bacterial Detection Rate and Surgical Outcome in Povidone-Iodine Irrigation After Nasolacrimal Duct Intubation.Clinical ophthalmology (Auckland, N.Z.) · 2020Article
- Article
- Ocular bacterial infections at Quiha Ophthalmic Hospital, Northern Ethiopia: an evaluation according to the risk factors and the antimicrobial susceptibility of bacterial isolates.BMC infectious diseases · 2017Article
- Clinical significance of routine lacrimal sac biopsy during dacryocystorhinostomy: A comprehensive review of literature.Bosnian journal of basic medical sciences · 2017Review
- Role of Histomorphology and Chronic Inflammation Score in Chronic Dacryocystitis.Journal of clinical and diagnostic research : JCDR · 2016Article
- Microbiology of primary acquired nasolacrimal duct obstruction: simple epiphora, acute dacryocystitis, and chronic dacryocystitis.Clinical ophthalmology (Auckland, N.Z.) · 2016Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo analyze cases of obstruction of the nasolacrimal duct which creates a fertile environment for secondary bacterial infection and can result in dacryocystitis, which is a constant threat to cornea and orbital soft tissue and a potential source of endophthalmitis following intraocular surgery. The majority of obstructions of the lacrimal excretory outflow system are acquired ones occurring in adulthood and involving the distal parts of the system. Acquired obstruction may be primary/idiopathic or secondary to a wide variety of infectious, inflammatory, traumatic, mechanical, toxic or neoplastic causes mimicking idiopathic inflammation. These cases are treated by dacryocystorhinostomy (DCR).
methodsThe present study was conducted to determine the histopathologic, immunohistochemical and current microbiologic characteristics of lacrimal sac specimens in patients undergoing external dacryocystorhinostomy.
resultsNon-specific lacrimal sac pathology was present in all 33 cases and 81.8% of the cases showed moderate chronic inflammation with a chronic inflammatory score (CIS) ranging between 4 and 6, whereas 12.12% showed severe inflammatory changes with a CIS of 7. Mild degree of inflammation was seen in 6.06% with a CIS of 3. The total prevalence of gram-positive, gram-negative, and culture-negative samples were 59.4%, 37.5%, and 3% respectively.
conclusionNon-specific chronic inflammation with fibrosis is indeed the most commonly reported histopathological finding in lacrimal sac wall biopsy specimens.
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