Evidence map›Paper›PMID 24392124›Full record

ArticlePloS one2014

Uptake of community-based HIV testing during a multi-disease health campaign in rural Uganda.

Gabriel Chamie, Dalsone Kwarisiima, Tamara D Clark, Jane Kabami, Vivek Jain, Elvin Geng, Laura B Balzer, Maya L Petersen, Harsha Thirumurthy, Edwin D Charlebois and 2 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01864603 (Sustainable East Africa Research in Community Health), which is not on this map. Cited by 54 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 4 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01864603 nacompletednot on this map

Sustainable East Africa Research in Community Health

TypeinterventionalSponsorUniversity of California, San FranciscoRan2013 to 2021Enrolled150,395ConditionsHIV, Tuberculosis, Hypertension, DiabetesArmsUniversal ART in a streamlined care model, Annual Community Health Campaigns, Targeted PrEP and Targeted testing interventions, Baseline community-based HIV and multi-disease testing
3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 4 syntheses or guidelines pooled it, 74 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Gabriel ChamieHIV/AIDS Division, Department of Medicine, San Francisco General Hospital, University of California San Francisco, San Francisco, United States of America ; Makerere University-University of California San Francisco (MU-UCSF) Research Collaboration, Uganda ; The Sustainable East Africa Research in Community Health (SEARCH) Consortium.
Dalsone KwarisiimaMakerere University-University of California San Francisco (MU-UCSF) Research Collaboration, Uganda ; The Sustainable East Africa Research in Community Health (SEARCH) Consortium ; Mulago-Mbarara Joint AIDS Program, Kampala and Mbarara, Uganda.
Tamara D ClarkHIV/AIDS Division, Department of Medicine, San Francisco General Hospital, University of California San Francisco, San Francisco, United States of America ; Makerere University-University of California San Francisco (MU-UCSF) Research Collaboration, Uganda ; The Sustainable East Africa Research in Community Health (SEARCH) Consortium.
Jane KabamiMakerere University-University of California San Francisco (MU-UCSF) Research Collaboration, Uganda ; The Sustainable East Africa Research in Community Health (SEARCH) Consortium.
Vivek JainHIV/AIDS Division, Department of Medicine, San Francisco General Hospital, University of California San Francisco, San Francisco, United States of America ; Makerere University-University of California San Francisco (MU-UCSF) Research Collaboration, Uganda ; The Sustainable East Africa Research in Community Health (SEARCH) Consortium.
Elvin GengHIV/AIDS Division, Department of Medicine, San Francisco General Hospital, University of California San Francisco, San Francisco, United States of America ; Makerere University-University of California San Francisco (MU-UCSF) Research Collaboration, Uganda ; The Sustainable East Africa Research in Community Health (SEARCH) Consortium.
Laura B BalzerThe Sustainable East Africa Research in Community Health (SEARCH) Consortium ; School of Public Health, University of California, Berkeley, United States of America.
Maya L PetersenThe Sustainable East Africa Research in Community Health (SEARCH) Consortium ; School of Public Health, University of California, Berkeley, United States of America.
Harsha ThirumurthyThe Sustainable East Africa Research in Community Health (SEARCH) Consortium ; Gillings School of Global Public Health, University of North Carolina at Chapel Hill, United States of America.
Edwin D CharleboisMakerere University-University of California San Francisco (MU-UCSF) Research Collaboration, Uganda ; The Sustainable East Africa Research in Community Health (SEARCH) Consortium ; Center for AIDS Prevention Studies, Department of Medicine, University of California San Francisco, San Francisco, United States of America.
Moses R KamyaMakerere University-University of California San Francisco (MU-UCSF) Research Collaboration, Uganda ; The Sustainable East Africa Research in Community Health (SEARCH) Consortium ; Department of Medicine, School of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.
Diane V HavlirHIV/AIDS Division, Department of Medicine, San Francisco General Hospital, University of California San Francisco, San Francisco, United States of America ; Makerere University-University of California San Francisco (MU-UCSF) Research Collaboration, Uganda ; The Sustainable East Africa Research in Community Health (SEARCH) Consortium.
MUJHU Research Collaboration · UGSan Francisco General Hospital · USUniversity of California, Berkeley · USUniversity of California, San Francisco · USUniversity of North Carolina at Chapel Hill · US

Funding

Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
Reducing Failure-to-Initiate ART: Streamlined ART Start Strategy (START)U01AI099959 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HAVLIR, DIANE V · 2012 to 2016
$39.7M
San Francisco Vaccine and Prevention UnitUM1AI069496 · NIAID · PUBLIC HEALTH FOUNDATION ENTERPRISES · PI Susan Buchbinder, Diane V Havlir · 2012 to 2026
$30.5M
Carolina Population CenterR24HD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MORGAN, SAMUEL PHILIP · 2005 to 2014
$10.0M
NIAID NIH HHS 3P30AI027763-19S1NIAID NIH HHS P30 AI027763NIAID NIH HHS U01 AI099959NIAID NIH HHS UM1 AI069496NICHD NIH HHS R24 HD050924
6 · The paper itself

Abstract

backgroundThe high burden of undiagnosed HIV in sub-Saharan Africa is a major obstacle for HIV prevention and treatment. Multi-disease, community health campaigns (CHCs) offering HIV testing are a successful approach to rapidly increase HIV testing rates and identify undiagnosed HIV. However, a greater understanding of population-level uptake is needed to maximize effectiveness of this approach.

methodsAfter community sensitization and a census, a five-day campaign was performed in May 2012 in a rural Ugandan community. The census enumerated all residents, capturing demographics, household location, and fingerprint biometrics. The CHC included point-of-care screening for HIV, malaria, TB, hypertension and diabetes. Residents who attended vs. did not attend the CHC were compared to determine predictors of participation.

resultsOver 12 days, 18 census workers enumerated 6,343 residents. 501 additional residents were identified at the campaign, for a total community population of 6,844. 4,323 (63%) residents and 556 non-residents attended the campaign. HIV tests were performed in 4,795/4,879 (98.3%) participants; 1,836 (38%) reported no prior HIV testing. Of 2674 adults tested, 257 (10%) were HIV-infected; 125/257 (49%) reported newly diagnosed HIV. In unadjusted analyses, adult resident campaign non-participation was associated with male sex (62% male vs. 67% female participation, p = 0.003), younger median age (27 years in non-participants vs. 32 in participants; p<0.001), and marital status (48% single vs. 71% married/widowed/divorced participation; p<0.001). In multivariate analysis, single adults were significantly less likely to attend the campaign than non-single adults (relative risk [RR]: 0.63 [95% CI: 0.53-0.74]; p<0.001), and adults at home vs. not home during census activities were significantly more likely to attend the campaign (RR: 1.20 [95% CI: 1.13-1.28]; p<0.001).

conclusionsCHCs provide a rapid approach to testing a majority of residents for HIV in rural African settings. However, complementary strategies are still needed to engage young, single adults and achieve universal testing.

Indexed as

Community Health ServicesHealth PromotionPoint-of-Care SystemsRural Health ServicesAdolescentAdultAgedChildChild, PreschoolComorbidityFemaleHIV InfectionsHumansMaleMass ScreeningMiddle Aged

Identifiers

PMID24392124
PMCPMC3879307
OpenAlexW1970884078

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.