ArticlePloS one2014
Type-II myocardial infarction--patient characteristics, management and outcomes.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
70 citing papers in PubMed, 3 syntheses or guidelines pooled it, 160 citations in OpenAlex.
- Pooled it
- A systematic review on the triggers and clinical features of type 2 myocardial infarction.Clinical cardiology · 2019Pooled it
- Variations on classification of main types of myocardial infarction: a systematic review and outcome meta-analysis.Clinical research in cardiology : official journal of the German Cardiac Society · 2019Pooled it
- Sex differences in secondary preventive follow-up after coronary heart events.BMC cardiovascular disorders · 2023Trial
- Platelet Count and Mean Platelet Volume at the Time of and After Acute Myocardial Infarction.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis · 2017Trial
- Type 2 Myocardial Infarction: Navigating Diagnostic Pathways and Therapeutic Crossroads Between Invasive and Conservative Strategies.Journal of clinical medicine · 2026Review
- Article
- Type 2 myocardial infarction: challenges in diagnosis and treatment.European heart journal · 2025Review
- Prevalence of Myocardial Infarction With Obstructive and Non-Obstructive Coronary Arteries in a Middle-Aged Population With Chronic Airflow Limitation: A Cross-Sectional Study.International journal of chronic obstructive pulmonary disease · 2025Article
- Unexpected Grave's-induced acute myocardial infarction in a young female, a literature review based on a case report.International journal of emergency medicine · 2024Article
- Exploring the Molecular Adaptations, Benefits, and Future Direction of Exercise Training: Updated Insights into Cardiovascular Health.Journal of functional morphology and kinesiology · 2024Review
- Type 2 Myocardial Infarction in a Sub-Saharan Africa Population: Challenging the Current Concepts-Data From REACTIV.Journal of the American Heart Association · 2024Observational
- Prevalence, Predictors, and Outcomes of Type 2 NSTEMI in Hospitalized Patients With COVID-19.Journal of the American Heart Association · 2024Article
- Myocardial infarction in a population-based cohort of patients with biopsy-confirmed giant cell arteritis in southern Sweden.RMD open · 2024Article
- Polygenic risk scores point toward potential genetic mechanisms of type 2 myocardial infarction in people with HIV.International journal of cardiology · 2023Article
- Type 2 Myocardial Infarction and Long-Term Mortality Risk Factors: A Retrospective Cohort Study.Advances in therapy · 2023Article
- Diagnostic value of high sensitivity cardiac troponin T (hs-cTnT) in dialysis patients with myocardial infarction.Frontiers in cardiovascular medicine · 2023Article
- Review
- Sex-related differences in the management and outcomes of patients hospitalized with ST-elevation myocardial infarction: a comparison within four European myocardial infarction registries.European heart journal open · 2022Article
- Patterns and outcomes of invasive management of type 2 myocardial infarction in the United States.Coronary artery disease · 2022Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundType-II MI is defined as myocardial infarction (MI) secondary to ischemia due to either increased oxygen demand or decreased supply. This categorization has been used for the last five years, yet, little is known about patient characteristics and clinical outcomes. In the current work we assessed the epidemiology, causes, management and outcomes of type II MI patients.
methodsA comparative analysis was performed between patients with type-I and type-II MI who participated in two prospective national Acute Coronary Syndrome Israeli Surveys (ACSIS) performed in 2008 and 2010.
resultsThe surveys included 2818 patients with acute MI of whom 127 (4.5%) had type-II MI. The main causes of type-II MI were anemia (31%), sepsis (24%), and arrhythmia (17%). Patients with type-II MI tended to be older (75.6±12 vs. 63.8±13, p<0.0001), female majority (43.3% vs. 22.3%, p<0.0001), had more frequently impaired functional level (45.7% vs. 17%, p<0.0001) and a higher GRACE risk score (150±32 vs. 110±35, p<0.0001). Patients with type-II MI were significantly less often referred for coronary interventions (36% vs. 89%, p<0.0001) and less frequently prescribed guideline-directed medical therapy. Mortality rates were substantially higher among patients with type-II MI both at thirty-day (13.6% vs. 4.9%, p<0.0001) and at one-year (23.9% vs. 8.6%, p<0.0001) follow-ups.
conclusionsPatients with type-II compared to type-I MI have distinct demographics, increased prevalence of multiple comorbidities, a high-risk cardiovascular profile and an overall worse outcome. The complex medical condition of this cohort imposes a great therapeutic challenge and specific guidelines with recommended medical treatment and invasive strategies are warranted.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.