ReviewFrontiers in plant science2013
Phosphatidic acid, a versatile water-stress signal in roots.
Review in Frontiers in plant science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 79 citations in OpenAlex.
- Integrating QTL mapping with transcriptome analysis uncovers candidate genes of ear length in maize.BMC plant biology · 2026Article
- Response of hidden architects to salt stress.Planta · 2025Review
- KRN5b regulates maize kernel row number through mediating phosphoinositol signalling.Plant biotechnology journal · 2024Article
- Understanding of Plant Salt Tolerance Mechanisms and Application to Molecular Breeding.International journal of molecular sciences · 2024Review
- Ectopic Expression of Distinct PLC Genes Identifies 'Compactness' as a Possible Architectural Shoot Strategy to Cope with Drought Stress.Plant & cell physiology · 2024Article
- Phosphatidic acid-regulated SOS2 controls sodium and potassium homeostasis in Arabidopsis under salt stress.The EMBO journal · 2023Article
- Phosphatidic acid modulates MPK3- and MPK6-mediated hypoxia signaling in Arabidopsis.The Plant cell · 2022Article
- Arabidopsis PLDζ1 and PLDζ2 localize to post-Golgi membrane compartments in a partially overlapping manner.Plant molecular biology · 2022Article
- Salinity tolerance mechanisms and their breeding implications.Journal, genetic engineering & biotechnology · 2021Review
- Link between Lipid Second Messengers and Osmotic Stress in Plants.International journal of molecular sciences · 2021Review
- Transcriptome and Metabolome Analyses Reveal Potential Salt Tolerance Mechanisms Contributing to Maintenance of Water Balance by the Halophytic GrassFrontiers in plant science · 2021Article
- Silencing of phosphoinositide dependent protein kinase orthologs reduces hypersensitive cell death inPlant biotechnology (Tokyo, Japan) · 2020Article
- Phospholipid Signaling Is a Component of the Salicylic Acid Response in Plant Cell Suspension Cultures.International journal of molecular sciences · 2020Review
- Regulation of ABA-Non-Activated SNF1-Related Protein Kinase 2 Signaling Pathways by Phosphatidic Acid.International journal of molecular sciences · 2020Article
- Membrane lipids are involved in plant response to oxygen deprivation.Plant signaling & behavior · 2020Article
- Role for ArabidopsisFrontiers in plant science · 2018Article
- Bioorthogonal click chemistry for fluorescence imaging of choline phospholipids in plants.Plant methods · 2018Article
- Article
- Regulation of mRNA decay in plant responses to salt and osmotic stress.Cellular and molecular life sciences : CMLS · 2017Review
- Transcriptional Responses in Root and Leaf ofFrontiers in plant science · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adequate water supply is of utmost importance for growth and reproduction of plants. In order to cope with water deprivation, plants have to adapt their development and metabolism to ensure survival. To maximize water use efficiency, plants use a large array of signaling mediators such as hormones, protein kinases, and phosphatases, Ca(2) (+), reactive oxygen species, and low abundant phospholipids that together form complex signaling cascades. Phosphatidic acid (PA) is a signaling lipid that rapidly accumulates in response to a wide array of abiotic stress stimuli. PA formation provides the cell with spatial and transient information about the external environment by acting as a protein-docking site in cellular membranes. PA reportedly binds to a number of proteins that play a role during water limiting conditions, such as drought and salinity and has been shown to play an important role in maintaining root system architecture. Members of two osmotic stress-activated protein kinase families, sucrose non-fermenting 1-related protein kinase 2 and mitogen activated protein kinases were recently shown bind PA and are also involved in the maintenance of root system architecture and salinity stress tolerance. In addition, PA regulates several proteins involved in abscisic acid-signaling. PA-dependent recruitment of glyceraldehyde-3-phosphate dehydrogenase under water limiting conditions indicates a role in regulating metabolic processes. Finally, a recent study also shows the PA recruits the clathrin heavy chain and a potassium channel subunit, hinting toward additional roles in cellular trafficking and potassium homeostasis. Taken together, the rapidly increasing number of proteins reported to interact with PA implies a broad role for this versatile signaling phospholipid in mediating salt and water stress responses.
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Registered trials
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