Evidence map›Paper›PMID 24391595›Full record

ReviewFrontiers in physiology2013

Neuro-hormonal effects of physical activity in the elderly.

Grazia D Femminella, Claudio de Lucia, Paola Iacotucci, Roberto Formisano, Laura Petraglia, Elena Allocca, Enza Ratto, Loreta D'Amico, Carlo Rengo, Gennaro Pagano and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
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  8. Adrenal adrenoceptors in heart failure.Frontiers in physiology · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Grazia D FemminellaDepartment of Translational Medical Sciences, University of Naples Federico II Naples, Italy.
Claudio de LuciaDepartment of Translational Medical Sciences, University of Naples Federico II Naples, Italy.
Paola IacotucciDepartment of Translational Medical Sciences, University of Naples Federico II Naples, Italy.
Roberto FormisanoDepartment of Translational Medical Sciences, University of Naples Federico II Naples, Italy.
Laura PetragliaDepartment of Translational Medical Sciences, University of Naples Federico II Naples, Italy.
Elena AlloccaDepartment of Translational Medical Sciences, University of Naples Federico II Naples, Italy.
Enza RattoDepartment of Translational Medical Sciences, University of Naples Federico II Naples, Italy.
Loreta D'AmicoDepartment of Translational Medical Sciences, University of Naples Federico II Naples, Italy.
Carlo RengoDepartment of Translational Medical Sciences, University of Naples Federico II Naples, Italy ; Division of Cardiology, Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Telese Terme (BN) Telese Terme, Italy.
Gennaro PaganoDepartment of Translational Medical Sciences, University of Naples Federico II Naples, Italy.
Domenico BonaduceDepartment of Translational Medical Sciences, University of Naples Federico II Naples, Italy.
Giuseppe RengoDepartment of Translational Medical Sciences, University of Naples Federico II Naples, Italy ; Division of Cardiology, Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Telese Terme (BN) Telese Terme, Italy.
Nicola FerraraDepartment of Translational Medical Sciences, University of Naples Federico II Naples, Italy ; Division of Cardiology, Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Telese Terme (BN) Telese Terme, Italy.
University of Naples Federico II · ITFondazione Salvatore Maugeri · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thanks to diagnostic and therapeutic advances, the elderly population is continuously increasing in the western countries. Accordingly, the prevalence of most chronic age-related diseases will increase considerably in the next decades, thus it will be necessary to implement effective preventive measures to face this epidemiological challenge. Among those, physical activity exerts a crucial role, since it has been proven to reduce the risk of cardiovascular diseases, diabetes, obesity, cognitive impairment and cancer. The favorable effects of exercise on cardiovascular homeostasis can be at least in part ascribed to the modulation of the neuro-hormonal systems implicated in cardiovascular pathophysiology. In the elderly, exercise has been shown to affect catecholamine secretion and biosynthesis, to positively modulate the renin-angiotensin-aldosterone system and to reduce the levels of plasma brain natriuretic peptides. Moreover, drugs modulating the neuro-hormonal systems may favorably affect physical capacity in the elderly. Thus, efforts should be made to actually make physical activity become part of the therapeutic tools in the elderly.

Indexed as

brain natriuretic peptideelderlyphysical activityrenin-angiotensin-aldosterone systemsympathetic nervous system

Identifiers

PMID24391595
PMCPMC3868730
OpenAlexW2159608083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.