ArticlePLoS genetics2014
Comparative evolutionary and developmental dynamics of the cotton (Gossypium hirsutum) fiber transcriptome.
Article in PLoS genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
86 citing papers in PubMed, 181 citations in OpenAlex.
- Harnessing polyploidy for climate-resilient crops: Lessons from the evolutionary model, allotetraploid cotton.Proceedings of the National Academy of Sciences of the United States of America · 2026Review
- Conservation and divergence of abiotic stress-responsive gene co-expression networks in diploid and tetraploid cotton.Frontiers in plant science · 2026Article
- Integrated metabolomic and transcriptomic analyses identify MYB genes regulating key metabolites and agronomic traits in upland cotton Gossypium hirsutum.Nature genetics · 2025Article
- Genetic basis and role of exotic accessions in cultivated cotton fiber quality improvement.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Review
- A high-resolution model of gene expression during Gossypium hirsutum (cotton) fiber development.BMC genomics · 2025Article
- The role of DNA content in shaping chromatin architecture and gene expression.The Plant journal : for cell and molecular biology · 2025Article
- Regulatory networks of coresident subgenomes during rapid fiber cell elongation in upland cotton.Plant communications · 2024Article
- Characteristics of duplicated gene expression and DNA methylation regulation in different tissues of allopolyploid Brassica napus.BMC plant biology · 2024Article
- Global gene expression profile and functional analysis reveal the conservation of reproduction-associated gene networks in Gossypium hirsutum.Plant reproduction · 2024Article
- Evolutionary Dynamics of Chromatin Structure and Duplicate Gene Expression in Diploid and Allopolyploid Cotton.Molecular biology and evolution · 2024Article
- Comparative Transcriptomic Analysis ofPlants (Basel, Switzerland) · 2024Article
- Article
- A comprehensive overview of cotton genomics, biotechnology and molecular biological studies.Science China. Life sciences · 2023Review
- Genetic dissection of lint percentage in short-season cotton using combined QTL mapping and RNA-seq.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Article
- Comparative transcriptional and co-expression network analysis of two upland cotton accessions with extreme phenotypic differences reveals molecular mechanisms of fiber development.Frontiers in plant science · 2023Article
- Analysis of transcriptome data and quantitative trait loci enables the identification of candidate genes responsible for fiber strength in Gossypium barbadense.G3 (Bethesda, Md.) · 2022Article
- Spatial and Temporal Transcriptomic Heredity and Asymmetry in an Artificially Constructed Allotetraploid Wheat (AADD).Frontiers in plant science · 2022Article
- Gene expression and DNA methylation altering lead to the high oil content in wild allotetraploid peanut (Frontiers in plant science · 2022Article
- Concomitant Expression Evolution of Cell Wall Cytoskeletal Geneic Triad(s) Controls Floral Organ Shape and Fiber Emergence in Cotton (Frontiers in plant science · 2022Article
26 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The single-celled cotton (Gossypium hirsutum) fiber provides an excellent model to investigate how human selection affects phenotypic evolution. To gain insight into the evolutionary genomics of cotton domestication, we conducted comparative transcriptome profiling of developing cotton fibers using RNA-Seq. Analysis of single-celled fiber transcriptomes from four wild and five domesticated accessions from two developmental time points revealed that at least one-third and likely one-half of the genes in the genome are expressed at any one stage during cotton fiber development. Among these, ~5,000 genes are differentially expressed during primary and secondary cell wall synthesis between wild and domesticated cottons, with a biased distribution among chromosomes. Transcriptome data implicate a number of biological processes affected by human selection, and suggest that the domestication process has prolonged the duration of fiber elongation in modern cultivated forms. Functional analysis suggested that wild cottons allocate greater resources to stress response pathways, while domestication led to reprogrammed resource allocation toward increased fiber growth, possibly through modulating stress-response networks. This first global transcriptomic analysis using multiple accessions of wild and domesticated cottons is an important step toward a more comprehensive systems perspective on cotton fiber evolution. The understanding that human selection over the past 5,000+ years has dramatically re-wired the cotton fiber transcriptome sets the stage for a deeper understanding of the genetic architecture underlying cotton fiber synthesis and phenotypic evolution.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.